The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome

NCT ID: NCT05742776

Last Updated: 2025-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-23

Study Completion Date

2026-03-01

Brief Summary

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The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients and to compare the findings with healthy controls.

Detailed Description

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Carpal tunnel syndrome is the most common form of entrapment neuropathies. Anatomically, the roof of the carpal tunnel consists of carpal bones, it is located under the transverse carpal ligament, and there are 9 tendon packs of the forearm flexors and the median nerve. Clinically, sensory (paresthesia and hypoesthesia), motor deficits and pain occur in the distribution of the median nerve secondary to mechanical compression and local ischemia.

With the increase in the severity of the disease, entrapment neuropathy, whose symptoms are more pronounced at night, negatively affects the daily life of the person. Waking up at night due to paresthesia is one of the diagnostic criteria for carpal tunnel syndrome. However, the mechanism linking CTS with insomnia is unclear.

The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients.

Conditions

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Musculoskeletal Diseases Median Nerve Disease Carpal Tunnel Syndrome Ultrasound Sleep Quality

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patient Group

CTS Patients

Assessment of Sleep Quality

Intervention Type OTHER

Assessment of Sleep Quality

Control Group

Healthy Individuals

Assessment of Sleep Quality

Intervention Type OTHER

Assessment of Sleep Quality

Interventions

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Assessment of Sleep Quality

Assessment of Sleep Quality

Intervention Type OTHER

Assessment of Sleep Quality

Assessment of Sleep Quality

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with CTS according to the criteria of the American Academy of Neurology

Exclusion Criteria

* Patients with radiculopathy, brachial plexopathy, thoracic outlet syndrome and traumatic nerve injury that may affect the median nerve
* History of Carpal tunnel surgery
* Pregnancy
* Malignancy
* Thyroid diseases
* Amyloidosis
* Systemic lupus erythematosus, Rheumatoid arthritis, Systemic sclerosis, Gout, Dermatomyositis, Polymyositis
* Obstructive sleep apnea
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Afyonkarahisar Health Sciences University

OTHER

Sponsor Role lead

Responsible Party

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Nuran Eyvaz

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nuran EYVAZ, MD

Role: PRINCIPAL_INVESTIGATOR

Afyonkarahisar Health Sciences University

Ali İzzet AKÇİN, MD

Role: PRINCIPAL_INVESTIGATOR

Afyonkarahisar Health Sciences University

Locations

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Afyonkarahisar Health Sciences University

Afyonkarahisar, Afyonkarahi̇sar, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Ali İzzet AKÇİN, MD

Role: CONTACT

+905469347374

Nuran EYVAZ, MD

Role: CONTACT

+905334262442

Facility Contacts

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Ali İzzet AKÇİN, MD

Role: primary

+905469347374

Nuran EYVAZ, MD

Role: backup

+905334262442

References

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Padua L, Coraci D, Erra C, Pazzaglia C, Paolasso I, Loreti C, Caliandro P, Hobson-Webb LD. Carpal tunnel syndrome: clinical features, diagnosis, and management. Lancet Neurol. 2016 Nov;15(12):1273-1284. doi: 10.1016/S1474-4422(16)30231-9. Epub 2016 Oct 11.

Reference Type BACKGROUND
PMID: 27751557 (View on PubMed)

Okkesim CE, Serbest S, Tiftikci U, Cirpar M. Prospective evaluation of preoperative and postoperative sleep quality in carpal tunnel release. J Hand Surg Eur Vol. 2019 Mar;44(3):278-282. doi: 10.1177/1753193418808182. Epub 2018 Nov 4.

Reference Type BACKGROUND
PMID: 30394830 (View on PubMed)

Kaymak B, Ozcakar L, Cetin A, Candan Cetin M, Akinci A, Hascelik Z. A comparison of the benefits of sonography and electrophysiologic measurements as predictors of symptom severity and functional status in patients with carpal tunnel syndrome. Arch Phys Med Rehabil. 2008 Apr;89(4):743-8. doi: 10.1016/j.apmr.2007.09.041.

Reference Type BACKGROUND
PMID: 18374007 (View on PubMed)

Other Identifiers

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CTSPUKI23

Identifier Type: -

Identifier Source: org_study_id

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