The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome

NCT ID: NCT05047367

Last Updated: 2021-09-27

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 149 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-01-13
• Study Completion Date: 2021-07-20

Brief Summary

The most common entrapment neuropathy symptoms, the diagnosis of CTS, is determined by examination findings and by means of the results of electro-diagnostic test. With an increase in disease severity, trap neuropathy, whose symptoms are more pronounced at night, negatively affects the daily life of the person. Deterioration in sleep quality may cause depression and anxiety. Conflicting results have been found in the studies related to these findings. However, no study was found in which daytime sleepiness was evaluated in terms of CTS. The investigators aim in this study is to evaluate the relationship between CTS severity and depression, anxiety, sleep quality and daytime sleepiness.

Detailed Description

Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy with an incidence of 2.7-4%. CTS, resulting from compression of the median nerve in the wrist, clinically progresses with tingling, numbness matching the nerve trace, and motor deficit in the presence of progressive nerve damage. Accordingly, the incidence of neuropathic pain is increasing. In addition to these symptoms mentioned, electro-diagnostic tests are used for diagnostic purposes and to determine the severity of nerve compression, and as a result, there are different types of classification, but most commonly CTS is classified as mild, moderate and severe. This classification is of great importance for the regulation of the follow-up and treatment protocol and making the association of existing complaints with the disease. Studies have shown that approximately 80% of CTS patients wake up at night due to numbness in the hand, resulting in deterioration in sleep quality. Impairment of sleep quality may cause increased sympathetic nervous system activity and awakening of physical and psychological stressors. Deterioration in sleep quality may cause depression and anxiety. Conflicting results have been found in the studies related to these findings. However, no study was found in which daytime sleepiness was evaluated in terms of CTS. The investigators aim in this study is to evaluate the relationship between CTS severity and depression, anxiety, sleep quality and daytime sleepiness. This study;149 patients with a diagnosis of CTS were prospectively included in the study. Electro-diagnostic test results were used to determine the severity of the disease. In this context, Boston CTS rating scale was used to evaluate the functional and symptomatic effects, Pittsburgh sleep quality scale and Epworth sleepiness scale were used to evaluate sleep quality and daytime sleepiness, and pain DETECT questionnaire was used to evaluate pain type.

Conditions

Carpal Tunnel Syndrome; Depressive Symptoms; Sleepiness; Anxiety; Sleep; Pain, Neuropathic

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

single-group studies

A total of 149 patients diagnosed with CTS, 126 female and 23 male, were included in the study

cross-sectional survey study

Intervention Type: BEHAVIORAL

Beck Depression Scale, Beck Anxiety Scale for psychological evaluation, Visual Analogue Scale and PainDETECT Questionnaire for pain, Pittsburgh Sleep Quality Scale and Epworth Sleepiness Scale for sleep quality

Interventions

cross-sectional survey study

Beck Depression Scale, Beck Anxiety Scale for psychological evaluation, Visual Analogue Scale and PainDETECT Questionnaire for pain, Pittsburgh Sleep Quality Scale and Epworth Sleepiness Scale for sleep quality

Intervention Type: BEHAVIORAL

Other Intervention Names

all patients were filled out forms for sleep quality and psychological evaluation

Eligibility Criteria

Inclusion Criteria

• Patients aged 18-75 years diagnosed with CTS.
• Patients who were mentally able to respond to the assessment questionnaires were also included

Exclusion Criteria

• Clinical diagnosis of cervical radiculopathy/plexopathy findings
• Pregnancy
• Diabetes mellitus
• thyroid diseases
• amyloidosis
• collagen tissue diseases
• Obstructive sleep apnea
• History of the upper extremity trauma

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cumhuriyet University

OTHER

Sponsor Role: lead

Responsible Party

Emel Güler

Asst Prof

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Emel Guler

Sivas, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Rubin G, Orbach H, Rinott M, Rozen N. Relationship between electrodiagnostic findings and sleep disturbance in carpal tunnel syndrome: A controlled objective and subjective study. J Int Med Res. 2020 Feb;48(2):300060519862673. doi: 10.1177/0300060519862673. Epub 2019 Jul 18.

Reference Type: RESULT

PMID: 31319726 (View on PubMed)

Other Identifiers

2021-01/39

Identifier Type: -

Identifier Source: org_study_id