Effects of Oxytocin and Vasopressin on Moral Decision Making

NCT ID: NCT04890470

Last Updated: 2023-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-02

Study Completion Date

2022-12-12

Brief Summary

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To determine whether the neuropeptide oxytocin (OXT) and vassopressin (AVP) influence moral decision making

Detailed Description

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In a double-blind, between- subject placebo (PLC) controlled design, subjects will first complete a series of questionnaires in terms of mood, clinical symptoms, and traits. After that their moral judgment and emotion towards both verbal descriptions of moral dilemma scenarios and pictures of specific interpersonal ones will be assessed and the effect of intranasal OXT and AVP between both male and female healthy subjects will be investigated.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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oxytocin group

subjects with oxytocin treatment

Group Type EXPERIMENTAL

Oxytocin

Intervention Type DRUG

intranasal administration of oxytocin (24 IU)

vasopressin group

subjects with vasopressin treatment

Group Type EXPERIMENTAL

Vasopressin

Intervention Type DRUG

intranasal administration of vasopressin (20 IU)

placebo group

subjects with placebo treatment

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

intranasal administration of placebo

Interventions

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Oxytocin

intranasal administration of oxytocin (24 IU)

Intervention Type DRUG

Vasopressin

intranasal administration of vasopressin (20 IU)

Intervention Type DRUG

Placebo

intranasal administration of placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria

* pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Keith Kendrick

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Keith M. Kendrick

Role: PRINCIPAL_INVESTIGATOR

University of Electronic Science and Technology of China

Locations

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Xiaoxiao Zheng

Sichuan, Sichuan, China

Site Status

Countries

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China

Other Identifiers

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UESTC-neuSCAN-78

Identifier Type: -

Identifier Source: org_study_id

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