Effects of Intranasal Oxytocin on Striatal Functional Connectivity

NCT ID: NCT03128203

Last Updated: 2017-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

135 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-09-30

Study Completion Date

2017-04-30

Brief Summary

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To investigate whether 40 IU of intranasal oxytocin treatment can influence the resting-state functional connectivity in healthy males.

Detailed Description

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In a double-blind, between-subject, placebo controlled design, investigators plan to investigate the effects of oxytocin treatment on resting-state functional connectivity.

Subject will receive either intranasal oxytocin or placebo administration and go through a seven-minute resting-state scan in MRI scanner to test whether oxytocin changes functional connectivity in the brain. Trait anxiety and mood questionnaires will be administered as control variables.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Oxytocin

Group Type EXPERIMENTAL

Oxytocin

Intervention Type DRUG

Oxytocin, intranasally administrated

Placebo

Group Type PLACEBO_COMPARATOR

Placebos

Intervention Type DRUG

Saline, intranasally administrated

Interventions

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Oxytocin

Oxytocin, intranasally administrated

Intervention Type DRUG

Placebos

Saline, intranasally administrated

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* healthy subjects without past or current psychiatric or neurological disorders

Exclusion Criteria

* with MRI Contraindications
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Benjamin Becker

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Benjamin Becker, Dr.

Role: PRINCIPAL_INVESTIGATOR

School of Life Science and Technology, University of Electronic Science and Technology of China

Locations

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School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Site Status

Countries

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China

Other Identifiers

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UESTC-neuSCAN-36

Identifier Type: -

Identifier Source: org_study_id

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