Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
EARLY_PHASE1
72 participants
INTERVENTIONAL
2016-01-31
2017-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
The Modulatory Effect of Oxytocin on Interoception
NCT03074409
Effects of Oxytocin on Reinforcement Learning and Interoception
NCT05245708
Effect of Oxytocin Nasal Inhalation on Empathy Analgesia
NCT05823441
Oxytocin's Effect on the Advantageous- and Disadvantageous-inequity
NCT06405737
Effects of Intranasal Oxytocin on Striatal Functional Connectivity
NCT03128203
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
In a between-subject, randomized double-blind design, subjects will be either administered intranasal OXT or placebo nasal spray (40 IU). 45 minutes after administration subjects will undergo (fMRI) tasks of empathic processing.
During the tasks subjects will be shown empathy inducing stimuli, and the behavioral and neural response in terms of cognitive, emotional and indirect emotional empathy will be assessed.
Before the administration of treatment, validated questionnaires assessing potential confounding variables, such as depression (Becks Depression Inventory (BDI)) or mood (Positive And Negative Affect Scale (PANAS)) will be administered to the subjects.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
FACTORIAL
BASIC_SCIENCE
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
male participants - oxytocin nasal spray
male participants - receiving a single dose of 40 IU intranasal oxytocin
Oxytocin
40 international units
female participants - oxytocin nasal spray
female participants - receiving a single dose of 40 IU intranasal oxytocin
Oxytocin
40 international units
male participants - placebo nasal spray
male participants - receiving a single dose of 40 IU intranasal placebo
Placebo
40 international units
female participants - placebo nasal spray
female participants - receiving a single dose of 40 IU intranasal placebo
Placebo
40 international units
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Oxytocin
40 international units
Placebo
40 international units
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* no smoking at least 12 hours before experiment
* no alcohol, coffee or other stimulant drinking at least 12 hours before experiment
Exclusion Criteria
* pregnancy
* uterine cavity operations
* use of medication
* acute physical disorder
18 Years
30 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Electronic Science and Technology of China
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Keith Kendrick
PhD
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Keith Kendrick, PhD
Role: PRINCIPAL_INVESTIGATOR
China,Sichuan, School of Life Science and Technology,University of Electronic Science and Technology
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
School of Life Science and Technology,University of Electronic Science and Technology
Chengdu, Sichuan, China
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
UESTC-neuSCAN-03
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.