Neural Correlates of Real World Spatial Navigation in Humans

NCT ID: NCT04874220

Last Updated: 2025-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-30

Study Completion Date

2026-06-30

Brief Summary

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The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.

Detailed Description

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Conditions

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Memory, Delayed

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Interventions

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Deep Brain Stimulation

Deep brain stimulation will be used

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 12 years of age or older and has undergone RNS system placement
* Willing to provide informed consent and participate the study
* Ability to read and write English fluently

Exclusion Criteria

* Unwilling to provide informed consent
Minimum Eligible Age

12 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Neurological Disorders and Stroke (NINDS)

NIH

Sponsor Role collaborator

University of California, Los Angeles

OTHER

Sponsor Role lead

Responsible Party

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Nanthia Suthana

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nanthia Suthana, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, Los Angeles

Locations

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University of California Los Angeles

Los Angeles, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Sonja Hiller

Role: CONTACT

3107947517

Facility Contacts

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Sonja Hiller

Role: primary

310-794-7517

Other Identifiers

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20-001459

Identifier Type: -

Identifier Source: org_study_id

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