The Ontario Multi-Regional Hospital COVID-19 Registry (COREG)- Recovery Trajectory Sub-study
NCT ID: NCT04868864
Last Updated: 2021-05-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
200 participants
OBSERVATIONAL
2021-05-15
2022-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Moderate to severe COVID-19 infection
COVID-19 patients with radiographic changes on CXR or CT which had not resolved or had persistent hypoxia due to COVID-19 at the time of discharge will be enrolled. All participants will undergo a LDCT and PFT.
CT scan
Non-enhanced LDCT scans of the thorax will be taken using standard technology on helical CT system
Pulmonary Function Test
Standard pulmonary function testing will be conducted by trained pulmonary technologists following the American Thoracic Society standards
Persistent LDCT or PFT abnormalities
Participants with abnormalities on LDCT and or PFT will be invited to continue with a follow-up sub-study. This will involve follow up with repeated LDCT and PFT at subsequent time points to monitor and manage the abnormalities detected until the abnormalities fully resolve or to the last time point at 9 months of the study.
CT scan
Non-enhanced LDCT scans of the thorax will be taken using standard technology on helical CT system
Pulmonary Function Test
Standard pulmonary function testing will be conducted by trained pulmonary technologists following the American Thoracic Society standards
Interventions
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CT scan
Non-enhanced LDCT scans of the thorax will be taken using standard technology on helical CT system
Pulmonary Function Test
Standard pulmonary function testing will be conducted by trained pulmonary technologists following the American Thoracic Society standards
Eligibility Criteria
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Inclusion Criteria
* Patients with evidence of unresolved radiographic changes or persistent hypoxemia.
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Gilead Sciences
INDUSTRY
Hamilton Health Sciences Corporation
OTHER
Responsible Party
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MyLinh Duong
Professor Department of Medicine
Principal Investigators
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Mylinh Duong, MD
Role: PRINCIPAL_INVESTIGATOR
McMaster University Hospital
Locations
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Juravinski Hospital
Hamilton, Ontario, Canada
Countries
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Central Contacts
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Facility Contacts
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Mylinh Duong, MD PhD
Role: primary
Other Identifiers
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13161
Identifier Type: -
Identifier Source: org_study_id
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