Microbiome Analysis of Skin and Airway Samples and Effect of Face Masks

NCT ID: NCT04894422

Last Updated: 2021-05-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-15

Study Completion Date

2023-03-15

Brief Summary

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The goal of this study is to optimize two methods for microbiome analysis of skin and upper airway samples (16S amplicon sequencing and Shotgun sequencing). In addition, the researchers will investigate whether there is an effect of wearing a face mask on the microbial communities of the skin and upper airways. The volunteers will self-collect swabs of the skin and upper airways (nose and/or throat). Bacterial DNA and/or total RNA will be isolated and the microbial communities will be investigated with 16S amplicon sequencing and shotgun metagenomic sequencing.

Detailed Description

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Conditions

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Healthy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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No face mask

Volunteers who did not wear a face mask

Observational intervention

Intervention Type OTHER

Voluntarily (not) wearing a face mask (cotton or surgical) for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Cotton face mask

Voluntarily wearing a cotton face mask for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Observational intervention

Intervention Type OTHER

Voluntarily (not) wearing a face mask (cotton or surgical) for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Surgical face mask

Voluntarily wearing a surgical face mask for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Observational intervention

Intervention Type OTHER

Voluntarily (not) wearing a face mask (cotton or surgical) for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Interventions

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Observational intervention

Voluntarily (not) wearing a face mask (cotton or surgical) for 4 hours, following the government's guidelines during the COVID-19 pandemic.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult age 18 at the start of the study

Exclusion Criteria

* Pregnant women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universiteit Antwerpen

OTHER

Sponsor Role collaborator

University Hospital, Antwerp

OTHER

Sponsor Role lead

Responsible Party

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Sarah Lebeer

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sarah Lebeer, Prof.

Role: PRINCIPAL_INVESTIGATOR

Universiteit Antwerpen

Locations

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University of Antwerp and University Hospital Antwerp

Antwerp, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Sarah Lebeer, Prof.

Role: CONTACT

+3232653285

Veronique Verhoeven, Prof. Dr.

Role: CONTACT

+3232652518

Facility Contacts

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Sarah Lebeer, Professor

Role: primary

+32 3 265 32 85

Lize Delanghe

Role: backup

+32 3 265 32 17

Other Identifiers

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B3002021000072

Identifier Type: -

Identifier Source: org_study_id

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