AV Node Isolation in Atrial Fibrillation vs. Modulation by "Pace and Ablate" Strategy

NCT ID: NCT04859933

Last Updated: 2022-08-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-01

Study Completion Date

2022-02-28

Brief Summary

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AV-node ablation (AVNA) is a common therapy option for rate control strategy of permanent atrial fibrillation with numerous side effects. The investigators hypothesised that an isolation of the AV node is concomitant with less occurrence of new bundle brunch blocks, more frequent preservation and higher rate of escape rhythm compared to AVNA. This retrospective study includes 20 patients being treated with AV-node isolation (AVNI) and 40 historical AVNA-controls. Among others these two methods were compared regarding escape rhythm, delta QRS, procedure time, ablation points, fluoroscopy time and total dose area product (DAP).

Detailed Description

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Conditions

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Atrial Fibrillation AV Node Ablation Escape; Rhythm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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AVNA group

Group of historical controls beeing treated with AV-node ablation

AV-node ablation

Intervention Type PROCEDURE

Right sided ablation of the AV-node

AVNI group

Inculudes all patients beeing treated with AV-node isolation

AV-node isolation

Intervention Type PROCEDURE

Abaltion performed in the right atrium isolating the AV-node from the atrium

Interventions

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AV-node isolation

Abaltion performed in the right atrium isolating the AV-node from the atrium

Intervention Type PROCEDURE

AV-node ablation

Right sided ablation of the AV-node

Intervention Type PROCEDURE

Other Intervention Names

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AVNI AVNA

Eligibility Criteria

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Inclusion Criteria

* paroxysmal, persistend or permanent atrial fibrillation; indication for AVNA

Exclusion Criteria

* other indications for AVNA than atrial fibrillation as AVNRT, atrial flutter, atrial tachycardia
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heart and Diabetes Center North-Rhine Westfalia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum

Bad Oeynhausen, , Germany

Site Status

Countries

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Germany

Other Identifiers

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HDZ_ER_003_GI

Identifier Type: -

Identifier Source: org_study_id

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