The Influence of Genetic Predisposition on Outcome After Catheter Ablation of Atrial Fibrillation.
NCT ID: NCT04753541
Last Updated: 2021-02-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
1000 participants
OBSERVATIONAL
2020-11-01
2023-06-30
Brief Summary
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Detailed Description
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The most common cause for AF recurrence is still incomplete isolation of the pulmonary veins, on the other hand, only 80% of paroxysmal and 60 % of persistent patients can successfully be cured from atrial fibrillation (despite of isolated pulmonary veins after multiple ablation procedures).
By now, non-procedure related predictive risk factors, resulting in recurrence of atrial fibrillation after catheter ablation, are only partially identified, such as obesity, hypertension and sleep apnea.
In the past year several genetic risk alleles were identified, which are associated with atrial fibrillation. By now the relation between genetic risk, which is determined for every patient by its specific genotype and the outcome of catheter ablation in paroxysmal and persistent atrial fibrillation has not yet been investigated.
The aim is to investigate the influence of genetic risk for the recurrence of atrial fibrillation after catheter ablation.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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no intervention
this is not an interventional study
Eligibility Criteria
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Inclusion Criteria
* written informed consent
Exclusion Criteria
* prior left atrial ablation
18 Years
ALL
No
Sponsors
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Deutsches Herzzentrum Muenchen
OTHER
Responsible Party
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Principal Investigators
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Bourier Felix, MD
Role: PRINCIPAL_INVESTIGATOR
Deutsches Herzzentrum München
Locations
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Deutsches Herzzentrum Muenchen
Munich, , Germany
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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304/20 S-KH
Identifier Type: -
Identifier Source: org_study_id
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