Biomarkers in Patients Undergoing Atrial Fibrillation Ablation

NCT ID: NCT03388333

Last Updated: 2019-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-31

Study Completion Date

2019-04-30

Brief Summary

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The investigators aim to find biomarkers to determine the success of pulmonary vein isolation for the treatment of atrial fibrillation.

Detailed Description

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The investigators perform an observational study in patients undergoing pulmonary vein ablation to treat atrial fibrillation. Additionally, electrophysiological procedures not related to pulmonary vein isolation are also followed. The aim of the study is finding biomarkers that are able to predict short-term outcome of the procedure.The primary endpoint is defined as reoccurrences of atrial fibrillation within the first three months after pulmonary vein isolation.

Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Atrial fibrillation ablation group

Patients undergoing catheter ablation for the treatment of atrial fibrillation.

Catheter Ablation

Intervention Type PROCEDURE

Electrophysiological study group

Patients undergoing a diagnostic electrophysiological study without ablation.

No interventions assigned to this group

Atrial flutter ablation group

Patients undergoing catheter ablation of right atrial flutter at the cavotricuspid isthmus.

Catheter Ablation

Intervention Type PROCEDURE

Interventions

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Catheter Ablation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with atrial fibrillation scheduled for pulmonary vein isolation with either radiofrequency of cryoballoon
* patients scheduled for an electrophysiological study without ablation
* patients with a catheter ablation at the cavotricuspid isthmus for the treatment of right atrial flutter

Exclusion Criteria

* patients with concurrent pulmonary vein isolation and ablation of the cavotricuspid isthmus
* Acute myocardial infarction, coronary artery bypass graft surgery or open heart surgery within less than 3 months prior to inclusion
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitätsklinikum Hamburg-Eppendorf

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. Christian Meyer

Prof. Dr. Christian Meyer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christian Meyer, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Germany Department of Cardiology - Electrophysiology, University Heart Centre

Locations

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Department of Cardiology - Electrophysiology, University Heart Centre, University Hospital Hamburg-Eppendorf

Hamburg, , Germany

Site Status

Countries

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Germany

Other Identifiers

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D4/17-06

Identifier Type: -

Identifier Source: org_study_id

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