Role of Subsequent Atrial Tachycardia in Mechanisms of Persistent AF

NCT ID: NCT01896570

Last Updated: 2013-07-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Brief Summary

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In this study, the investigators aim to examine the prognostic role of subsequent Atrial Tachycardias (ATs) in the mechanisms of atrial fibrillation (AF). Therefore, the investigators compare patients who were randomly assigned to either undergo cardioversion after AF has been terminated to AT or further ablation until the achievement of sinus rhythm.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Group A: cardioversion at AT

after achievement of AT, pts were cardioverted

No interventions assigned to this group

Group B: ablation to SR

After AT has been achieved, all subsequent AT were ablated with the endpoint of procedural SR termination

Catheter ablation of subsequent atrial tachycardia

Intervention Type PROCEDURE

Interventions

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Catheter ablation of subsequent atrial tachycardia

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* persistent AF for at least 1 months,
* age \> 18 years,
* refractory to drug therapy,
* no prior ablation

Exclusion Criteria

* prior AF ablation
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johannes Gutenberg University Mainz

OTHER

Sponsor Role lead

Responsible Party

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Thomas Rostock

Univ.-Prof. Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital Eppendorf, Dept. of Electrophysiology

Hamburg, , Germany

Site Status

Countries

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Germany

References

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Rostock T, Salukhe TV, Hoffmann BA, Steven D, Berner I, Mullerleile K, Theis C, Bock K, Servatius H, Sultan A, Willems S. Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial. Circ Arrhythm Electrophysiol. 2013 Dec;6(6):1059-65. doi: 10.1161/CIRCEP.113.001019. Epub 2013 Oct 25.

Reference Type DERIVED
PMID: 24162833 (View on PubMed)

Other Identifiers

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Ciritical endpoint HH

Identifier Type: -

Identifier Source: org_study_id

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