Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT)

NCT ID: NCT04827316

Last Updated: 2024-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

4200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-01

Study Completion Date

2031-02-01

Brief Summary

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In this study the investigators retrospectively and prospectively collect information from enrolled subjects undergoing CCTA and evaluate the association of cardiac and non-cardiac imaging with laboratory markers and clinical data including outcome.

Detailed Description

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In this study the investigators retrospectively and prospectively collect information from enrolled subjects through a period of a total of 10 years to evaluate multidimensional associations between phenotypic manifestations of cardiovascular disease via CCTA and cardiac and non-cardiac imaging, serum biomarkers, demographic and clinical information, clinical presentation (cross-sectional), therapy changes (time-varying) and their ability to predict mortality and MACE (major adverse cardiac event ) (longitudinal) in patients clinically indicated for CCTA.

The aim is to establish a comprehensive cross-sectional, time-varying and longitudinal data collection for individuals undergoing clinically-indicated CCTA to date in order to apply novel multiparametric approaches to determine cardiovascular significance to clinically-important patient-centered events. For data collection this registry will follow a standard CRF (case report form) structure, so to enable the merging of this data-set with other international registries, which might contribute in overcoming some gaps of knowledge from previous CCTA studies.

Conditions

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Coronary Artery Disease Coronary Arteriosclerosis Coronary; Ischemic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients undergoing clinically indicated CCTA

Patients undergoing clinically indicated CCTA

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adult individual \>18 years
* Undergoing clinically indicated CCTA
* Signed informed consent or waiver

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Zürich

OTHER

Sponsor Role collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Christoph Gräni, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Cardiology, University Hospital Bern,

Locations

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Department of Cardiology, University Hospital Bern, Inselspital, Bern

Bern, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Christoph Gräni, MD, PHD

Role: CONTACT

+41 31 632 4508

Facility Contacts

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Christoph Gräni, Prof

Role: primary

+41316324508

Other Identifiers

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2021-00058

Identifier Type: -

Identifier Source: org_study_id

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