Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt

NCT ID: NCT04809454

Last Updated: 2021-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-31

Study Completion Date

2022-03-31

Brief Summary

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Thyroxin a vital hormone for life lot of body functions depend on proper functioning on pituitary thyroid axis. it exists in two major forms Thyroxine (T4) and (T3) , each of them containing two iodine atoms on their inner (tyrosine) ring. Synthesis of reasonable quantities of thyroid hormones requires adequate iodine intake to allow sufficient thyroidal uptake. The World Health Organization (WHO) recommendation for daily intake of iodine is 150 μg for children ≥12 years and adults, and 250 μg for pregnant and lactating women. However as we know optimum amount of iodine is required for normal pituitary thyroid axis like wise excessive intake may cause over functioning of axis hence over production of hormone that can be manifested both clinically and biochemically.

This study is designed to observe the frequency of over hyperthyroidism in patients taking iodinated salt.

Detailed Description

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All patients presenting to endocrine clinic fulfilling inclusion and exclusion criteria will be recruited. They will be examined, their vitals including blood pressure pulse will be noted, thyroid clinical examination including eye signs and thyroid status will be done biochemical Thyroid profile (TSH, Free T3 \& Free T4) will be noted in predesigned proforma.

Statistical Analysis will be done ,after data is entered in Statistical Package for the Social Sciences (SPSS) version 25 .qualitative data will be presented as frequencies and percentages while quantitative data will be presented as mean medians and standard deviations.

Conditions

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Thyroid Dysfunction

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

1. All patients presenting with biochemical hyperthyroidism
2. Who are taking Iodinated salt.
3. Treatment naïve patients
4. Both genders included
5. All patients who can give consent (18-60 years)

Exclusion Criteria

1\) Pregnant females 2) Lactating mothers

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Services Institute of Medical Sciences, Pakistan

OTHER_GOV

Sponsor Role lead

Responsible Party

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Mehwish Iftikhar

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mehwish Iftikhar

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Central Contacts

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Mehwish Iftikhar, FCPS Endocrinologyy

Role: CONTACT

923004291641

Amna Rizvi, FCPS Endocrinology

Role: CONTACT

923009463345

Facility Contacts

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Mehwish Iftikhar, FCPS Endocrinology

Role: primary

923004291641

Amna Rizvi, FCPS Endocrinology

Role: backup

923009463345

Other Identifiers

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1241985

Identifier Type: -

Identifier Source: org_study_id

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