Assessment of the 90-day Mortality Risk Score After VATS Lobectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2209 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2018-11-27

Brief Summary

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A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity \<60% (1 point) and operative time \>150 minutes (1 point), has been recently published. This study aims to assess the effectiveness and reliability of this risk model in a large, independent cohort of patients, in order to confirm its generalizability.

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Detailed Description

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From the Italian VATS Group Database, we selected patients who underwent video-assisted thoracoscopic lobectomy for non-small cell lung cancer. We calculated the aggregate risk score and the corresponding class of 90-day mortality risk for each patient. The correlation between risk classes and mortality rates was tested by Spearman's rho-test. Model calibration was evaluated by Hosmer-Lemeshow goodness-of-fit test.

Conditions

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Lung Cancer Surgery--Complications Morality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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VATS lobectomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Patients undergoing VATS lobectomy for non-small cell lung cancer

Exclusion Criteria

* Incomplete data for risk score calculation
* Tumor size \>5 cm
* Follow-up \<3 months
* Patients undergoing neoadjuvant treatment
* Patients undergoing extended resection

Eligible Sex

ALL

Accepts Healthy Volunteers

No