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Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival

NCT ID: NCT04663191

Last Updated: 2020-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

843 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-02

Study Completion Date

2020-12-03

Brief Summary

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Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer. The use of minimally invasive approaches has increased greatly over the last two decades \[either video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS)\], as they provide the patient with better outcomes than open thoracotomy. Minimally invasive VATS lobectomy for a standard case is generally a straightforward procedure for a well-trained surgical team, although concomitant preoperative pathologies or intraoperative findings/adverse events may result in technical difficulties, leading to intraoperative conversion, commonly by thoracotomy.

The investigators aimed to assess long-term outcomes in a consecutive cohort of patients treated by anatomical pulmonary resection either using VATS, VATS requiring intraoperative conversion to thoracotomy, or upfront open thoracotomy for lung-cancer surgery.

Detailed Description

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Conditions

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Video-assisted Thoracoscopic Surgery Lung Cancer Lobectomy Survival Surgery

Keywords

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video-assisted thoracoscopic surgery lung-cancer surgery intraoperative conversion to open surgery lobectomy survival

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Full VATS

anatomical resection

Intervention Type PROCEDURE

Anatomical resection with systematic lymph-node dissection

VATS with conversion

anatomical resection

Intervention Type PROCEDURE

Anatomical resection with systematic lymph-node dissection

Thoracotomy upfront

anatomical resection

Intervention Type PROCEDURE

Anatomical resection with systematic lymph-node dissection

Interventions

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anatomical resection

Anatomical resection with systematic lymph-node dissection

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All consecutive patients treated by anatomical lobar pulmonary resection (lobectomy, bilobectomy) or anatomical sublobar pulmonary resection (segmentectomy) for non-small cell lung cancer (NSCLC), either by VATS (eventually with intraoperative conversion) or upfront thoracotomy.

Exclusion Criteria

* patients with non-anatomical pulmonary resection (wedge resection)
* patients with a histology other than NSCLC (benign or metastatic from another primitive cancer), stage IV NSCLC disease,
* patients with multiple primary NSCLC (synchronous or metachronous)
* patients with incomplete resection (R+)
* patient for whom a VATS approach was never considered
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens

Amiens, , France

Site Status

Countries

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France

Other Identifiers

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T38

Identifier Type: -

Identifier Source: org_study_id