Role of Ultrasound Assessment of Parasternal Intercostal Muscle Thickness During Weaning From Mechanical Ventilation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-01

Study Completion Date

2021-04-01

Brief Summary

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Assessment of the the parasternal intercostal muscles thickness by the ultrasonography as a weaning predictor of the mechanically ventilated patients

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Detailed Description

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impact of parasternal muscle thickness on the weaning process of the mechanically ventilated patients in ICU

Conditions

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Parasternal Intercostal Muscle Thickness Weaning From Mechanical Ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Mechanical Ventilated patients

All patients are invasively mechanically ventilated at least 24 hours, and are clinically stable as ready to undergo a spontaneous breathing trial.

Parasternal intercostal muscles thickness ultrasound indicies

Intervention Type DIAGNOSTIC_TEST

Parasternal intercostal muscles thickness ultrasound indicies includes:

* Parasternal Intercostals Thickness Fraction.
* Parasternal Intercostals Thickness at the End of Inspiration.
* Parasternal Intercostals thickness at the End of Expiration.

Interventions

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Parasternal intercostal muscles thickness ultrasound indicies

Parasternal intercostal muscles thickness ultrasound indicies includes:

* Parasternal Intercostals Thickness Fraction.
* Parasternal Intercostals Thickness at the End of Inspiration.
* Parasternal Intercostals thickness at the End of Expiration.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Diaphragmatic thickness

Eligibility Criteria

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Inclusion Criteria

Any patient invasively mechanically ventilated at least 24 hours on a pressure support mode who is clinically stable and ready to undergo a spontaneous breathing trial.

All patients will be:

* Alert.
* Afebrile.
* Adequate cough with absence of excessive tracheobronchial secretion.
* Fraction of inspired oxygen (FIO2) of \<50%.
* PEEP ≤8 cmH2O.
* PaO2/FiO2 \> 150.
* pH ≥7.35 and ≤7.45.
* Respiratory rate (RR) ≤35 breaths/min.
* Hemodynamically stable in the absence of vasopressors.
* Stable metabolic and endocrinal status.
* Euglycemic state.
* Adequate mentation (no sedation or stable neurologic patient).

Exclusion Criteria

Diaphragmatic paralysis (detected by ultrasonography).Patients\&Methods. 6

* Pregnant women.
* Age: \>= 18 years.
* Surgical dressings over measurement point which would preclude ultrasound exam.
* Underweight patients (Body mass index \<18.5 kg/m2).
* Morbidly obese patient (Body mass index ≥ 40 kg/m2).
* Primary neuro-muscular diseases.
* Central coditions with depressed central respiratory drive (encephalitis, and brainstem haemorrhage/ischaemia).
* Repiratory conditions with reduced pulmonary compliance (interstitial lung disease, pulmonary hemorrhage, and diffuse pulmonary infiltrates) or reduced chest wall compliance (kyphoscoliosis).
* Cardiac conditions with high risk of weaning induced pulmonary edema (congestive heart failure, cyanotic heart diease, pulmonary hypertension, and ischemic heart diease).
* Addict patients.
* Patients with psychiatric disease.

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No