MPV and NLR as Predictors of SBP Diagnosis

NCT ID: NCT04775420

Last Updated: 2023-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

332 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-01

Study Completion Date

2022-04-30

Brief Summary

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The aim of the study is to investigate the clinical utility of mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) as diagnostic markers for spontaneous bacterial peritonitis (SBP).

Detailed Description

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Conditions

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Spontaneous Bacterial Peritonitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group 1

Ascetic patients without spontaneous bacterial peritonitis

Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)

Intervention Type DIAGNOSTIC_TEST

MPV and NLR are easily accessible and inexpensive tests

Group 2

Ascetic patients with spontaneous bacterial peritonitis

Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)

Intervention Type DIAGNOSTIC_TEST

MPV and NLR are easily accessible and inexpensive tests

Interventions

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Measurement of mean platelet volume (MPV) and blood neutrophil to lymphocyte ratio (NLR)

MPV and NLR are easily accessible and inexpensive tests

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Decompensated liver cirrhosis ascetic patients.

Exclusion Criteria

* Immunocompromised patients.
* Patients who had received antibiotics before hospital admission.
* Patients on anticoagulant medications, NSAIDs, or oral contraceptive drugs.
* Patients with heart failure, diabetes mellitus, hypertension, hyperlipidemia, peripheral vascular disease, hematological disorders, and neoplastic disorders and patients with clinically overt hypothyroidism or hyperthyroidism or with clinically and laboratory-evident autoimmune diseases.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abudeif Abdelaal, MD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag Faculty of Medicine

Sohag, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Soh-Med-21-02-22

Identifier Type: -

Identifier Source: org_study_id

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