Platelet Count（PC）/Spleen Diameter(SD) Ratio to Predict the Variceal Haemorrhage in HBV Cirrhotic Patients in China
NCT ID: NCT02546414
Last Updated: 2015-09-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
150 participants
OBSERVATIONAL
2013-01-31
2015-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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Esophageal varices haemorrhage group
HBV hepatic cirrhosis with first esophageal varices haemorrhage were included and stratified using their Child-Pugh score. The platelet count were evaluated, and ultrasound was used to measure the longest diameter of the spleen. The platelet count(PC)/spleen diameter (SD)ratio was calculated and analyzed to determine whether it can predict the variceal haemorrhage. Upper gastrointestinal endoscopy was used as the gold standard.
Platelet count/spleen diameter ratio
Platelet count were evaluated by complete blood count, and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated
no haemorrhage but esophageal varice presence
HBV hepatic cirrhosis with no esophageal varices haemorrhage were included and upper gastrointestinal endoscopy were validate.They also stratified using their Child-Pugh score. The platelet count and longest diameter of the spleen were evaluated, The PC/SD ratio was calculated and analyzed to determine whether it can predict the variceal presence.
Platelet count/spleen diameter ratio
Platelet count were evaluated by complete blood count, and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated
no esophageal varice but cirrhotic
HBV hepatic cirrhosis with no esophageal varices were included and also validated by upper gastrointestinal endoscopy.They stratified using their Child-Pugh score. The platelet count and longest diameter of the spleen were evaluated,The PC/SD was calculated and analyzed to determine whether it can predict the variceal absence .
Platelet count/spleen diameter ratio
Platelet count were evaluated by complete blood count, and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated
Interventions
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Platelet count/spleen diameter ratio
Platelet count were evaluated by complete blood count, and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* use of medications for the primary prophylaxis of variceal bleeding,
* history of esophageal variceal bleeding,
* alcohol consumption within the admission and a history of ligation,
* sclerotherapy, and/or
* portal hypertension surgery
45 Years
85 Years
ALL
No
Sponsors
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RenJi Hospital
OTHER
Responsible Party
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Shengliang Chen
MD
Locations
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Renji Hospital
Shanghai, Shanghai Municipality, China
Countries
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Other Identifiers
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RJLIJINHUI-2015
Identifier Type: -
Identifier Source: org_study_id
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