Evaluation of Serum Amyloid A in Early Diagnosis of Spontaneous Bacterial Peritonitis
NCT ID: NCT02759497
Last Updated: 2017-06-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2016-03-31
2020-11-30
Brief Summary
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Serum amyloid A (SAA) and C-reactive protein (CRP) are acute-phase proteins predominantly produced and secreted by hepatocytes. Other cells including lymphocytes, monocytes, and macrophages can also produce these proteins. The induction of SAA and CRP synthesis is triggered by a number of cytokines, chiefly IL-6, which is released from a variety of cell types, but mainly from macrophages and monocytes at inflammatory sites
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Serum amyloid A level in SBP
serum amyloid A level
serum amyloid A level
serum amyloid A level (SAA)
Serum amyloid A level in cirrhosis
Serum amyloid A level
serum amyloid A level
serum amyloid A level (SAA)
Interventions
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serum amyloid A level
serum amyloid A level (SAA)
Eligibility Criteria
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Inclusion Criteria
* Laboratory findings
* Endoscopic results
* Ultrasound
* Histology
Exclusion Criteria
* Other infection e.grespiratory,UTI ,gastrointestinal and skin infection.
* Hepatocellular carcinoma
* Other extrahepatic malignancy e.g ; chest
* Any significant psychiatric illness or other medical comorbidity.
* Any degenerative diseases.
ALL
No
Sponsors
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Tanta University
OTHER
Responsible Party
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Sherief Abd-Elsalam
Consultant liver and GIT diseases- Tanta university hospital
Principal Investigators
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Rehab Badawi, Consultant
Role: PRINCIPAL_INVESTIGATOR
Hepatology and gastroenterology dept.-Tanta
Sherief Abd-Elsalam, Consultant
Role: STUDY_CHAIR
Division of Gastroenterology and Hepatology- Tanta
Walaa Elkhalawany, Consultant
Role: STUDY_CHAIR
Hepatology and gastroenterology dept.-Tanta
Reham Elkhouly, Consultant
Role: STUDY_CHAIR
Hepatology and gastroenterology dept.-Tanta
Mona Watany, Consultant
Role: STUDY_CHAIR
clinical pathology dept.-Tanta
Samah Soliman, Consultant
Role: STUDY_CHAIR
Hepatology and gastroenterology dept.-Tanta
Mai Khalaf, resident
Role: STUDY_CHAIR
hepatology dept.-Tanta
Locations
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Sherief Abd-Elsalam
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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sbp diagnosis
Identifier Type: -
Identifier Source: org_study_id
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