Effect of Osteopathic Manipulation Therapy on Pulmonary Function Testing in Children With Asthma

NCT ID: NCT04764877

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

58 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-01

Study Completion Date

2019-12-31

Brief Summary

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Objective To evaluate change in same-day pulmonary function testing in pediatric patients receiving OMT compared to those receiving usual care.

Methods For this study, we selected patients utilizing the following inclusion criteria: 1) ages 7-18 years, 2) a diagnosis of asthma, 3) patients receiving care at a primary care-based asthma clinic, and 4) those patients who had baseline spirometry. Selected patients were then randomized to either an OMT or a control group. We excluded patients who were experiencing an acute asthma exacerbation. Patients in the OMT group were treated with rib raising and suboccipital release, in addition to standard asthma care, while control group patients received standard care only. A second PFT was performed on both groups at the end of the visit. OMT was performed by multiple osteopathic pediatric residents who were specifically trained for the purposes of this study. Change in spirometry results (FVC, FEV1, FVC/FEV1, and FEF 25-75%) were then compared.

Detailed Description

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Objective To evaluate change in same-day pulmonary function testing in pediatric patients receiving OMT compared to those receiving usual care.

Methods For this study, we selected patients utilizing the following inclusion criteria: 1) ages 7-18 years, 2) a diagnosis of asthma, 3) patients receiving care at a primary care-based asthma clinic, and 4) those patients who had baseline spirometry. Selected patients were then randomized to either an OMT or a control group. We excluded patients who were experiencing an acute asthma exacerbation. Patients in the OMT group were treated with rib raising and suboccipital release, in addition to standard asthma care, while control group patients received standard care only. A second PFT was performed on both groups at the end of the visit. OMT was performed by multiple osteopathic pediatric residents who were specifically trained for the purposes of this study. Change in spirometry results (FVC, FEV1, FVC/FEV1, and FEF 25-75%) were then compared.

NOTE: The OMTs were done either by our OMM attending at that time (Dr. Wolf) or by residents trained by her for this study (Drs. Jones, Pe, Bryant and Regan,)

Conditions

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Asthma in Children

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Patients were randomized to either standard of care/teaching at our Hilltop Primary Care Center Asthma clinic OR to standard of care/teaching PLUS one time osteopathic manipulation focusing on improving lung expansion.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard Care

Standard teaching and physical exam for any patient that would be seen at our Hilltop Primary Care center asthma clinic. This included baseline PFTs. FOR THIS STUDY a second set of PFTs were obtained at the end of the visit

Group Type NO_INTERVENTION

No interventions assigned to this group

OMT arm

As above BUT with the addition of standardized OMT focusing on lung functionality. OMT provided by either our OMM attending at that time (Dr Wolf) or residents trained by her for this study (Drs. Regan, Jones, Pe and Bryant)

Group Type EXPERIMENTAL

Osteopathic Manipulative Medicine

Intervention Type OTHER

Provided 15-20 minute long OMT session for patients in the OMT arm

Interventions

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Osteopathic Manipulative Medicine

Provided 15-20 minute long OMT session for patients in the OMT arm

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age as noted above
* Diagnosis of asthma
* Scheduled for routine asthma care at our clinic
* at least one prior PFT done prior to this visit

Exclusion Criteria

* Clinical indication for pre- and post-bronchodilator spirometry on day of visit
* albuterol use w/in 8 hours of the visit
* oral steroid use in previous 2 weeks
* diagnosis of asthma exacerbation w/in prior 4 weeks
Minimum Eligible Age

7 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nationwide Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Alex Rakowsky

Assistant Professor Primary Care Pediatrics/Associate Residency Program Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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IRB #14-000667

Identifier Type: -

Identifier Source: org_study_id

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