Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2023-09-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

There is an unmet demand for the evaluation of nocturnal hypoventilation in children with NMD. An ambulatory screening tool that can reliably facilitate timely diagnosis and treatment in these children would be invaluable. If an ambulatory, at home, tcCO2 monitoring device is shown to be diagnostically accurate, sleep physicians would be able to triage children on existing waiting lists and optimize screening of nocturnal hypoventilation as recommended by international guidelines.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Home Initiation of Noninvasive Positive Pressure Ventilation in Children With Medical Complexity

NCT05881031

Sleep-Disordered Breathing

RECRUITING NA

Methods to Improve Expiratory Cough Flow and Lung Volume in Children With NMDs

NCT02342132

Neuromuscular Diseases

COMPLETED NA

Structured Light Plethysmography in Obstructive Airways Disease

NCT03499938

Pediatric Respiratory Diseases

COMPLETED

Overview: Use of Respiratory Support At Home in Children

NCT06692660

Sleep Apnea Syndromes in Children Obesity in Children Bronchopulmonary Dysplasia (BPD) +4 more

NOT_YET_RECRUITING

Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography

NCT02247700

Respiratory Failure Acute Respiratory Distress Syndrome Acute Lung Injury

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sleep Disorder; Breathing-Related Central Apnea Neuromuscular Diseases Obstructive Sleep Apnea

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Transcutaneous CO2 monitoring

Group Type EXPERIMENTAL

Transcutaneous CO2 monitoring

Intervention Type DEVICE

The aim is to assess the accuracy of ambulatory, at home, transcutaneous CO2 monitoring in pediatric Neuromuscular Disease (NMD).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Transcutaneous CO2 monitoring

The aim is to assess the accuracy of ambulatory, at home, transcutaneous CO2 monitoring in pediatric Neuromuscular Disease (NMD).

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* children with a confirmed diagnosis of NMD that meet criteria for evaluating SDB as per international recommendations
* lives within the greater Toronto area.

Exclusion Criteria

* known diagnosis of nocturnal hypoventilation
* current ventilatory support
* physician diagnosis of active upper respiratory tract infection (fever, increased cough, rhinorrhea, increased nasal congestion, sore throat, headache, malaise and/or sneezing).

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No