A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
NCT ID: NCT00308789
Last Updated: 2009-05-05
Study Results
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Basic Information
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TERMINATED
PHASE2
136 participants
INTERVENTIONAL
2006-04-30
2009-12-31
Brief Summary
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Detailed Description
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Comparisons: Biphasic NCPAP will be compared with continuous CPAP to see which better facilitates the extubation of preterm infants who weigh \</= 1250 grams at birth. The incidence of CLD, retinopathy of prematurity, sepsis, intraventricular haemorrhage, periventricular leucomalacia and necrotizing entercolitis will also be compared between the two groups.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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1
Biphasic NCPAP
Biphasic Infant flow NCPAP
Biphasic Nasal continuous positive airway pressure
2
Continuous CPAP
CPAP
Continuous positive airway pressure
Interventions
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Biphasic Infant flow NCPAP
Biphasic Nasal continuous positive airway pressure
CPAP
Continuous positive airway pressure
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Acquired nasal septum injury
* Congenital Heart Disease excluding Patent Ductus arteriosus
6 Months
ALL
No
Sponsors
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The Physicians' Services Incorporated Foundation
OTHER
Mount Sinai Hospital, Canada
OTHER
Principal Investigators
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Karel O'Brien, MB, FRCPC
Role: PRINCIPAL_INVESTIGATOR
MOUNT SINAI HOSPITAL
Locations
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Mount Sinai Hospital
Toronto, Ontario, Canada
Countries
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References
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O'Brien K, Campbell C, Brown L, Wenger L, Shah V. Infant flow biphasic nasal continuous positive airway pressure (BP- NCPAP) vs. infant flow NCPAP for the facilitation of extubation in infants' </= 1,250 grams: a randomized controlled trial. BMC Pediatr. 2012 Apr 4;12:43. doi: 10.1186/1471-2431-12-43.
Other Identifiers
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05-0258-A
Identifier Type: -
Identifier Source: org_study_id
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