Study Results
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View full resultsBasic Information
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COMPLETED
563 participants
OBSERVATIONAL
2021-03-15
2024-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Suspected Yaws Cases
Individuals with a lesion clinically suspected to be yaws and with evidence of positive treponemal and non-treponemal serology as assessed by point of care lateral flow tests (DPP Syphilis Screen and Confirm, Chembio)
PCR
qPCR for T.pallidum
LAMP
LAMP assay for T.pallidum
Interventions
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PCR
qPCR for T.pallidum
LAMP
LAMP assay for T.pallidum
Eligibility Criteria
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Inclusion Criteria
* Positive treponemal and non-treponemal antibodies assessed by the DPP Syphilis Screen and Confirm RDT
Exclusion Criteria
ALL
No
Sponsors
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Pasteur Institute abidjan
UNKNOWN
Centre Pasteur du Cameroun
OTHER
Noguchi Memorial Institute for Medical Research
OTHER
University of Freiburg
OTHER
MAST Group - Germany
UNKNOWN
Friedrich-Loeffler-Institut
UNKNOWN
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
OTHER
London School of Hygiene and Tropical Medicine
OTHER
Responsible Party
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Locations
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Centre Pasteur
Yaoundé, , Cameroon
Institut Pasteur
Abidjan, , Côte d’Ivoire
Noguchi Memorial Institute of Medical Research
Accra, , Ghana
Countries
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References
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Handley BL, Gonzalez-Beiras C, Tchatchouang S, Basing LA, Hugues KA, Bakheit M, Becherer L, Ries C, Njih Tabah E, Crucitti T, Borst N, Luert S, Frischmann S, Haerpfer T, Landmann E, Amanor I, Sylla A, Kouame-Sina MS, Ndzomo-Ngono JP, Tano A, Arhinful D, Awondo P, Ngazoa Kakou S, Eyangoh S, Addo KK, Harding-Esch EM, Knauf S, Mitja O, Marks M. LAMP4yaws: Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification - protocol for a cross-sectional, observational, diagnostic accuracy study. BMJ Open. 2022 Mar 29;12(3):e058605. doi: 10.1136/bmjopen-2021-058605.
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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LSHTM-21633
Identifier Type: -
Identifier Source: org_study_id
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