Evaluation of Adult Onset Still Disease Classification Criteria and Differential Diagnosis at Eighteen Months of Follow-up

NCT ID: NCT04750863

Last Updated: 2021-02-11

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 312 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-07-15
• Study Completion Date: 2021-02-01

Brief Summary

Adult Onset Still Disease (AOSD) is an acquired inflammatory disease of unknown etiology, presenting with non specific symptoms. Its diagnosis rely on sets of criteria, i.e. Fautrel Criteria and Yamaguchi Criteria. However, differential diagnosis might appear during follow-up of patients. The aim of this study is to assess diagnostic performance of Fautral and Yamaguchi Criteria after 18 months of follow-up, and to describe differential diagnosis appearing during follow-up.

Detailed Description

Adult Onset Still Disease (AOSD) is an acquired inflammatory disease of unknown etiology, presenting with non specific symptoms. Other conditions such as cancer, infection or other inflammatory disease might mimick its symptoms. Its diagnosis rely on sets of criteria, i.e. Fautrel Criteria and Yamaguchi Criteria. However, differential diagnosis might appear during follow-up after an initial diagnosis of AOSD. The aim of this study is to assess diagnostic performance of Fautral and Yamaguchi Criteria after 18 months of follow-up, and to describe differential diagnosis appearing during follow-up.

Conditions

Adult Onset Still Disease

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Interventions

diagnosis criteria performance

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• adults
• with glycosylated ferritin dosage for suspected adult onset still disease
• with at least 18 month of follow-up

Exclusion Criteria

• known infectious disease
• known cancer
• known active connective tissue disease or vasculitis

• Minimum Eligible Age: 18 Years
• Accepts Healthy Volunteers: No

Sponsors

Central Hospital, Nancy, France

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

2021PI001

Identifier Type: -

Identifier Source: org_study_id