Evaluation of Brain Damage Due to Coronary Angioplasty in Percutaneous Intervention Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-18

Study Completion Date

2020-03-25

Brief Summary

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This study examines the formation mechanism and patient-related factors of silent cerebral infarcts, whose importance has become increasingly recognized in patients undergoing percutaneous coronary intervention.

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Detailed Description

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This study was produced from the assistant's thesis and was previously accepted as a poster at EuroPCR 2020. We recently completed the full-length article.

This thesis study was supported by Ondokuzmayis University.

Conditions

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Silent Stroke Coronary Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Chronic Total Occlusion

Chronic total occlusion patients undergoing percutaneous coronary intervention.

Blood serum Neuron-specific Enolase measurement

Intervention Type DIAGNOSTIC_TEST

The Silent Brain Injury ratio was compared by measuring the Neuron-specific enzyme level with venous blood sampling from both patient groups before and after percutaneous coronary intervention.

Non-Chronic Total Occlusion

Non-Chronic total occlusion patients undergoing percutaneous coronary intervention.

Blood serum Neuron-specific Enolase measurement

Intervention Type DIAGNOSTIC_TEST

The Silent Brain Injury ratio was compared by measuring the Neuron-specific enzyme level with venous blood sampling from both patient groups before and after percutaneous coronary intervention.

Interventions

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Blood serum Neuron-specific Enolase measurement

The Silent Brain Injury ratio was compared by measuring the Neuron-specific enzyme level with venous blood sampling from both patient groups before and after percutaneous coronary intervention.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* CTO and Non-CTO patients undergoing percutaneous coronary intervention

Exclusion Criteria

* baseline NSE elevation
* acute coronary syndromes or cardiac surgery within 4 weeks
* patients with a cerebrovascular accident
* intracranial hemorrhage
* and head trauma
* central nervous system tumor
* degenerative central nervous system disorders and neuroendocrine tumors

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No