Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial
NCT ID: NCT04698317
Last Updated: 2021-10-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
40 participants
INTERVENTIONAL
2021-01-01
2021-07-01
Brief Summary
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Detailed Description
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(control group), the other 20 patients will be treated with the same surgical technique plus biodegradable gelatin sponge loaded with Beta-tricalcium phosphate socked in concentrated growth factors (test group).
Gingival index (GI), bleeding on probing, Probing pocket depth and clinical attachment level (CAL) will assessed at baseline, 3, and 6 months at the site to be treated. Cone beam radiographs evaluation will be taken at baseline, and 6 months after surgery.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
(control group), the other 20 patients will be treated with the same surgical technique plus biodegradable gelatin sponge loaded with Beta-tricalcium phosphate socked in concentrated growth factors (test group).
TREATMENT
TRIPLE
Study Groups
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beta-tricalcium phosphate plus concentrated growth factors
surgery plus biodegradable gelatin sponge loaded with Beta-tricalcium phosphate socked in concentrated growth factors (test group).
open flap debridement
Open flap for removal of diseased periodontal tissues and necrotic cementum
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate incorporating Concentrated Growth Factors in Periodontal Defect
beta tricalcium phosphate alone(control group)
surgery plus biodegradable gelatin/beta-tricalcium phosphate sponges alone. (control group),
open flap debridement
Open flap for removal of diseased periodontal tissues and necrotic cementum
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone in the Intrabony Periodontal Defect
Interventions
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open flap debridement
Open flap for removal of diseased periodontal tissues and necrotic cementum
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate incorporating Concentrated Growth Factors in Periodontal Defect
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone in the Intrabony Periodontal Defect
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* patients who had not received any medications for the previous six months that may interfere with periodontal tissue health or healing.
* Patients should demonstrate their ability to maintain good oral hygiene
Exclusion Criteria
* Medically compromised patients and systemic conditions precluding periodontal surgery.
* Subjects who do not comply with oral hygiene measures as evidenced in recall visits.
* Sites with tooth mobility
* Restoration or caries in the site to be treated or non-vital tooth
* Restoration or caries in the site to be treated or non-vital tooth
30 Years
50 Years
ALL
Yes
Sponsors
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Tanta University
OTHER
Responsible Party
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malak mohamed shoukheba
associate prof.
Principal Investigators
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malak m shoukheba
Role: PRINCIPAL_INVESTIGATOR
Cairo University
Locations
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Malak Mohamed Shoukheba
Tanta, , Egypt
Countries
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Other Identifiers
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≤ ≥ ° ± µ ™ ®
Identifier Type: -
Identifier Source: org_study_id
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