Clinical and Radiographic Assessment of Efficacy of Modified Minimally Invasive SurgicalTechnique (M-MIST) Alone and Combined With Enamel Matrix Proteins and Ox-derived Bone Graft in the Treatment of Single Bone Defects Between Teeth.
NCT ID: NCT07310732
Last Updated: 2025-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2022-03-01
2025-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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modified minimally invasive surgical technique
modified minimally invasive surgical technique
modified minimally invasive surgical technique alone in interdental area
modified minimally invasive surgical technique with emdogain
modified minimally invasive surgical technique plus emdogain
modified minimally invasive surgical technique with application of enamel matrix proteins in interdental area
modified minimally invasive surgical technique with emdogain and xenograft
modified minimally invasive surgical technique plus emdogain and xenograft
modified minimally invasive surgical technique with application of enamel matrix proteins and placement of bovine bone graft in interdental area
Interventions
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modified minimally invasive surgical technique
modified minimally invasive surgical technique alone in interdental area
modified minimally invasive surgical technique plus emdogain
modified minimally invasive surgical technique with application of enamel matrix proteins in interdental area
modified minimally invasive surgical technique plus emdogain and xenograft
modified minimally invasive surgical technique with application of enamel matrix proteins and placement of bovine bone graft in interdental area
Eligibility Criteria
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Inclusion Criteria
* patients with optimal compliance
Exclusion Criteria
* history of long-term use of medications
* allergic to medications
* pregnant or lactating women
* smokers/users of other tobacco products
18 Years
ALL
No
Sponsors
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Rungta College of Dental Sciences and Research
OTHER
Responsible Party
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Karthik Krishna M
Dean
Locations
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Department of Periodontics, Rungta College of Dental Sciences and Research
Bhilai, Chhattisgarh, India
Countries
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References
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Cortellini P, Tonetti MS. Clinical and radiographic outcomes of the modified minimally invasive surgical technique with and without regenerative materials: a randomized-controlled trial in intra-bony defects. J Clin Periodontol. 2011 Apr;38(4):365-73. doi: 10.1111/j.1600-051X.2011.01705.x. Epub 2011 Feb 8.
Cortellini P, Pini Prato G, Tonetti MS. Periodontal regeneration of human infrabony defects. II. Re-entry procedures and bone measures. J Periodontol. 1993 Apr;64(4):261-8. doi: 10.1902/jop.1993.64.4.261.
Cortellini P, Pini Prato G, Tonetti MS. Periodontal regeneration of human infrabony defects. I. Clinical measures. J Periodontol. 1993 Apr;64(4):254-60. doi: 10.1902/jop.1993.64.4.254.
Camelo M, Nevins ML, Lynch SE, Schenk RK, Simion M, Nevins M. Periodontal regeneration with an autogenous bone-Bio-Oss composite graft and a Bio-Gide membrane. Int J Periodontics Restorative Dent. 2001 Apr;21(2):109-19.
Other Identifiers
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RCDSR/IEC/MDS/2021/b-11
Identifier Type: -
Identifier Source: org_study_id