Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony Defects
NCT ID: NCT02507596
Last Updated: 2022-03-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
30 participants
INTERVENTIONAL
2015-04-30
2019-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Nano-crystalline hydroxyapatite silica gel
hydroxyapaptite bone graft with nano particle size in silica gel will be used to fill in the defect after opening a periodontal flap
Nano-crystalline hydroxyapatite silica gel
it is a type of synthetic bone graft.
Open flap debridement
an open periodontal flap without adding bone graft.
open flap debridement
a periodontal surgical procedure for the purpose of debridement.
Interventions
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Nano-crystalline hydroxyapatite silica gel
it is a type of synthetic bone graft.
open flap debridement
a periodontal surgical procedure for the purpose of debridement.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* having at least one site with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss as detected in periapical radiographs.
Exclusion Criteria
* Subjects had \<22 permanent teeth
* Having any given systemic disease
* Taking any type of medication and/or antibiotic therapy during the 3 months before the study
* Received periodontal treatment within the past 12 months Current or former smokers
35 Years
50 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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Noha Ayman Ghallab
Associate Professor of Oral Medicine and Periodontology
Principal Investigators
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Weam Battawy, MD
Role: STUDY_CHAIR
Lecturer of Oral Medicine and Periodontology
Noha Ghallab, MD
Role: PRINCIPAL_INVESTIGATOR
Associate Professor of Oral Medicine and Periodontology
Dalia AbdelHamid, MD
Role: STUDY_DIRECTOR
Associate Professor of Biomaterials
Riham Hamdy, MD
Role: STUDY_CHAIR
Associate Professor of Oral and Maxillofacial Radiology
Locations
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Faculty of Oral and Dental Medicine, Cairo University
Cairo, , Egypt
Countries
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References
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Reynolds MA, Aichelmann-Reidy ME, Branch-Mays GL, Gunsolley JC. The efficacy of bone replacement grafts in the treatment of periodontal osseous defects. A systematic review. Ann Periodontol. 2003 Dec;8(1):227-65. doi: 10.1902/annals.2003.8.1.227.
Heinz B, Kasaj A, Teich M, Jepsen S. Clinical effects of nanocrystalline hydroxyapatite paste in the treatment of intrabony periodontal defects: a randomized controlled clinical study. Clin Oral Investig. 2010 Oct;14(5):525-31. doi: 10.1007/s00784-009-0325-x. Epub 2009 Aug 13.
Kasaj A, Rohrig B, Zafiropoulos GG, Willershausen B. Clinical evaluation of nanocrystalline hydroxyapatite paste in the treatment of human periodontal bony defects--a randomized controlled clinical trial: 6-month results. J Periodontol. 2008 Mar;79(3):394-400. doi: 10.1902/jop.2008.070378.
Other Identifiers
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Nanobone_IBD
Identifier Type: -
Identifier Source: org_study_id
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