Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice

NCT ID: NCT04638452

Last Updated: 2021-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-08

Study Completion Date

2024-02-28

Brief Summary

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The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test in common practice.

Detailed Description

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The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test in common practice.

The aim is to analyse in an automated and standardised way video recording during a blood test performed as part of routine follow-up care for people presenting ASD (children and adults), qualitative data (type of emotion) and quantitative (intensity)

1. Emotional facial reactions
2. Behavioural reactions (video recording of participants' movements)
3. Physiological reactions (wireless smart watch worn on the wrist)
4. Psychological reactions (self and hetero questionaires) to characterize the signs of pain and anxiety associated with this situation)

Conditions

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Autism Spectrum Disorder

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Epidemiology
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Epidemiology

Video recording of face, body movements and physiological parameters (heart rate, conductance using a wireless watch) of the participants during the blood test Passing self and hetero questionnaires of temotion felt and perceived.

Group Type OTHER

Video & movements recording

Intervention Type BEHAVIORAL

Video recording of face, body movements and physiological parameters (heart rate, conductance using a wireless watch) of the participants during the blood test

Questionnaires

Intervention Type BEHAVIORAL

Passing self and hetero questionnaires of emotion felt and perceived.

Interventions

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Video & movements recording

Video recording of face, body movements and physiological parameters (heart rate, conductance using a wireless watch) of the participants during the blood test

Intervention Type BEHAVIORAL

Questionnaires

Passing self and hetero questionnaires of emotion felt and perceived.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

All participants :

* Person over 6 years of age
* Person who consent to participate in the study
* Membership of the social security scheme
* Person who not received analgesic treatment that may interfere with pain perception
* Person with medical prescription for blood sample

Participants with ASD :

* Person with ASD diagnosis
* If applicable, legal authority consent to participate in the study

Exclusion Criteria

All participants :

* Person with unstabilized drug therapy
* Person with acute or chronic pain
* Person with pathology or receiving a treatment which can have an impact in modification of the pain
* Person with oculomotor and/or neuro-motor disorders
* Pregnant or breastfeeding woman
* Person with deprivation of liberty
* Person who no consent to participate in the study or no consent to realised video recording

Participants without ASD :

* Protected adult
* Person with ASD diagnosis
Minimum Eligible Age

6 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Charles Perrens, Bordeaux

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anouck AMESTOY, MD

Role: STUDY_DIRECTOR

Physician

Locations

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Centre Hospitalier Charles PERRENS

Bordeaux, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Anouck AMESTOY, MD

Role: CONTACT

0556566719

helen SAVARIEAU

Role: CONTACT

0556563556

Facility Contacts

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Anouck AMESTOY, MD

Role: primary

05 56 56 67 19

References

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Hilton CL, Harper JD, Kueker RH, Lang AR, Abbacchi AM, Todorov A, LaVesser PD. Sensory responsiveness as a predictor of social severity in children with high functioning autism spectrum disorders. J Autism Dev Disord. 2010 Aug;40(8):937-45. doi: 10.1007/s10803-010-0944-8.

Reference Type RESULT
PMID: 20108030 (View on PubMed)

Hirvikoski T, Mittendorfer-Rutz E, Boman M, Larsson H, Lichtenstein P, Bolte S. Premature mortality in autism spectrum disorder. Br J Psychiatry. 2016 Mar;208(3):232-8. doi: 10.1192/bjp.bp.114.160192. Epub 2015 Nov 5.

Reference Type RESULT
PMID: 26541693 (View on PubMed)

Breau LM, Camfield CS, McGrath PJ, Finley GA. The incidence of pain in children with severe cognitive impairments. Arch Pediatr Adolesc Med. 2003 Dec;157(12):1219-26. doi: 10.1001/archpedi.157.12.1219.

Reference Type RESULT
PMID: 14662579 (View on PubMed)

Breau LM, Camfield CS, McGrath PJ, Finley GA. Risk factors for pain in children with severe cognitive impairments. Dev Med Child Neurol. 2004 Jun;46(6):364-71. doi: 10.1017/s001216220400060x.

Reference Type RESULT
PMID: 15174527 (View on PubMed)

Dubois A, Rattaz C, Pry R, Baghdadli A. [Autism and pain - a literature review]. Pain Res Manag. 2010 Jul-Aug;15(4):245-53. doi: 10.1155/2010/749275. French.

Reference Type RESULT
PMID: 20808970 (View on PubMed)

Allely CS. Pain sensitivity and observer perception of pain in individuals with autistic spectrum disorder. ScientificWorldJournal. 2013 Jun 13;2013:916178. doi: 10.1155/2013/916178. Print 2013.

Reference Type RESULT
PMID: 23843740 (View on PubMed)

Other Identifiers

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2020-A00693-36

Identifier Type: -

Identifier Source: org_study_id

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