Ivabradine Versus Propranolol for Induced Hypotension in Endoscopic Sinus Surgery

NCT ID: NCT04580342

Last Updated: 2020-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-15

Study Completion Date

2021-01-30

Brief Summary

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the study is designed to compare the effect of addition of oral Ivabradine, propranolol to general anesthesia aimed reduction in blood loss during functional endoscopic sinus surgery.

Detailed Description

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Conditions

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Hypotension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Ivabradine group

Group Type EXPERIMENTAL

oral Ivabradine

Intervention Type DRUG

Ivabradine group will receive ivabradine 5mg PO in the evening and 1 hour before anesthetic induction

propranolol group

Group Type EXPERIMENTAL

oral Propranolol

Intervention Type DRUG

propranolol group will receive propranolol 10 mg PO in the evening and 1 hour before anesthetic induction.

Interventions

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oral Ivabradine

Ivabradine group will receive ivabradine 5mg PO in the evening and 1 hour before anesthetic induction

Intervention Type DRUG

oral Propranolol

propranolol group will receive propranolol 10 mg PO in the evening and 1 hour before anesthetic induction.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age of 18 - 60 years.
* Patients of both genders.
* ASA grade I - II .

Exclusion Criteria

* Patient refusal.
* Any contraindication to medication included in the study .
* Patients with allergy to medication included in the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ahmed talaat ahmed aly

OTHER

Sponsor Role lead

Responsible Party

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Ahmed talaat ahmed aly

clinical professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Ahmed T Ahmed, A professor

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Locations

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Ahmed Talaat Ahmed

Asyut, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ahmed T Ahmed, A professor

Role: CONTACT

01062716629

Amal A Mohamed

Role: CONTACT

0102 175 9992

Facility Contacts

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Ahmed T Ahmed, A professor

Role: primary

01062716629

Amal A Mohamed

Role: backup

0102 175 9992

Other Identifiers

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ivabradine versus propranolol

Identifier Type: -

Identifier Source: org_study_id

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