Different Intra-abdominal Pressures and Optic Nerve Size

NCT ID: NCT04556877

Last Updated: 2020-09-21

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 78 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-06-15
• Study Completion Date: 2020-06-15

Brief Summary

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Detailed Description

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. This situation creates ischemia in the abdominal organs in the patient, decreases venous return as a result of inferior vena cava compression and leads to a decrease in cardiac output. In addition, intracranial pressure frequently increases as a result of the venous circulation being affected. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Conditions

Major Surgery; Intraabdominal Hypertension; Optic Nerve Congestion

Study Design

• Observational Model Type: CASE_CROSSOVER
• Study Time Perspective: PROSPECTIVE

Study Groups

Intraabdominal pressure under 12 mmHg

Patients with intraabdominal pressure under 12 mmHg

Intraabdominal pressure and optic nerve diameters

Intervention Type: PROCEDURE

Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Intraabdominal pressure between 12-20 mmHg

Patients with intraabdominal pressure between 12-20 mmHg

Intraabdominal pressure and optic nerve diameters

Intervention Type: PROCEDURE

Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Intraabdominal pressure over 20 mmHg

Patients with intraabdominal pressure over 20 mmHg

Intraabdominal pressure and optic nerve diameters

Intervention Type: PROCEDURE

Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Interventions

Intraabdominal pressure and optic nerve diameters

Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

Having had major abdominal surgery

Exclusion Criteria

1. pregnant patients

2. Patients whose bladder catheter cannot be inserted

3. Patients with diagnosed or suspected brain death

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Trakya University

OTHER

Sponsor Role: lead

Responsible Party

Prof Mehmet Turan Inal

Prof

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Trakya University

Edirne, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

TUTF 2018/230

Identifier Type: -

Identifier Source: org_study_id