Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
80 participants
INTERVENTIONAL
2019-04-30
2019-12-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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High Flow Anesthesia, Low Flow Anesthesia
. The patients were randomly allocated to one of the two groups of fresh gas flows using the closed-envelope technique: 2 L/min high flow and 0.5 L/min minimal flow. Group 1 (n = 40) was operated under high flow anesthesia with 50% O2 - 50% air at 2 L/min and desflurane at 1.1 MAC for the duration of the surgery. For anesthesia maintenance, Group 2 (n=40) was administered 50% oxygen - 50% air at 2 L/min and desflurane for 10-15 minutes. After reaching 1.1 MAC, it was switched to minimal flow with 50-60% oxygen- 40-50% air at 0.5 L/min and desflurane. 10 minutes before the end of the surgery, it was switched to high flow with 50% oxygen -50% air at 2 L/min.
The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
The patients were randomly allocated to one of the two groups of fresh gas flows using the closed-envelope technique: 2 L/min high flow and 0.5 L/min minimal flow.
Peroperetive Optic Nerve Sheath Diameter
Optic nerve sheath diameter measurements were performed by an experienced and the same anesthetist. In the measurements, the GE Healthcare Logiq e series USG device and 12-MHz linear probe were used. Longitudinal and transverse axis images were obtained on both eyelids while the patient was in the supine position. Measurements were taken 3 mm behind the optic nerve head
The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
The patients were randomly allocated to one of the two groups of fresh gas flows using the closed-envelope technique: 2 L/min high flow and 0.5 L/min minimal flow.
Interventions
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The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
The patients were randomly allocated to one of the two groups of fresh gas flows using the closed-envelope technique: 2 L/min high flow and 0.5 L/min minimal flow.
Eligibility Criteria
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Inclusion Criteria
* ASA I-II
* Who underwent laparotomic gynecological surgery
Exclusion Criteria
* Patients with decompensated diabetes, those with a fasting period of more than 12 hours -Acute alcohol intoxication
* Chronic alcohol use
* Who refuse to participate in the study
* Who are not cooperative, do not speak Turkish
* Who had known eye disease (glaucoma, retinal detachment), had a previous history of eye surgery,
* Increased intracranial pressure findings (intracranial lesion, previous cerebrovascular diseases
* Body mass index of \> 40kg/m2
* ASA \> III
18 Years
65 Years
ALL
Yes
Sponsors
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Bursa Yuksek Ihtisas Training and Research Hospital
OTHER_GOV
Responsible Party
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Anıl Onur
Principle İnvestigator
Principal Investigators
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Anıl Onur, MD
Role: PRINCIPAL_INVESTIGATOR
University of Health Science Bursa Yüksek Ihtisas Training and Research Hospital
H.Erkan Sayan, MD
Role: STUDY_DIRECTOR
University of Health Science Bursa Yüksek Ihtisas Training and Research Hospital
Tugba Onur, MD
Role: STUDY_CHAIR
University of Health Science Bursa Yüksek Ihtisas Training and Research Hospital
Umran Karaca, MD
Role: STUDY_CHAIR
University of Health Science Bursa Yüksek Ihtisas Training and Research Hospital
Canan Yılmaz, MD
Role: STUDY_CHAIR
University of Health Science Bursa Yüksek Ihtisas Training and Research Hospital
Locations
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University of Health Sciences Bursa Yüksek İhtisas Training and Research Hospital
Bursa, , Turkey (Türkiye)
Countries
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Other Identifiers
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2018/11-0
Identifier Type: -
Identifier Source: org_study_id