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Helicobacter Pylori Eradication and Irritable Bowel Syndrome: A Prospective Study

NCT ID: NCT04512898

Last Updated: 2020-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-10

Study Completion Date

2020-11-10

Brief Summary

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H. Pylori is frequently observed in patients with irritable bowel syndrome(IBS). However, the effect of H. pylori eradication on IBS is not clear.

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Detailed Description

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Patients with IBS symptoms using Rome IV criteria will be included. Testing for H. pylori will be done. Patients with H. pylori will receive triple therapy and followed after two weeks for eradication and assessment of IBS symptoms.

Conditions

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Irritable Bowel Syndrome

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Patients with IBS and have H. pylori
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patient with IBS

Patients with IBS and positive H. pylori.

Group Type EXPERIMENTAL

Triple therapy for H.pylori

Intervention Type DRUG

Triple therapy of proton pump inhibitors, clarithromycin and metronidazole.

Interventions

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Triple therapy for H.pylori

Triple therapy of proton pump inhibitors, clarithromycin and metronidazole.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients newly diagnosed with IBS and H.pylori

Exclusion Criteria

* Patients received previous treatment of H.pylori
* Patients receiving treatment for IBS.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Haidi Karam

Lecturer of Tropical Medicine and Gastroenterology

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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H. Pylori

Identifier Type: -

Identifier Source: org_study_id

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