Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser for Enlarged Facial Pores

NCT ID: NCT04470466

Last Updated: 2020-10-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-07-19
• Study Completion Date: 2020-10-12

Brief Summary

Facial pores are visible topographic features of the skin that reflect openings of pilosebaceous follicles, that may be enlarged causing distress to some individuals. Many patients desire treatment for this condition, which can be an early sign of skin aging. Therapeutic modalities include intense pulsed light, radiofrequency, dermabrasion, oral and topical retinoids, as well as chemical peeling. Lasers, as fractional CO2, short pulse and Q-switched Nd-YAG, can potentially be used in treatment of wide pores.

This study aims at the assessment and comparison of therapy with short pulsed and Q-switched Nd-YAG laser plus topical carbon with fractional CO2 laser in the management of wide facial pores.

Detailed Description

topical carbon cream will be applied to one side of the face in patients with wide facial pores, followed by 2 passes of short pulse 1064 ND:YAG laser, then one pass of Q-switched ND-YAG laser.

fractional CO2 laser will be performed to the other half of the face. the patients will receive 2 treatment sessions

Conditions

Skin Lesion

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

short pulse and Q-switched ND-YAG laser with topical carbon

Group Type: ACTIVE_COMPARATOR

short pulse and Q-switched ND-YAG laser with topical carbon

Intervention Type: DEVICE

application of topical carbon cream, followed by two passes of short pulse 1064 ND-YAG, then one pass of Q-switched 1064 ND-YAG on one side of the face

Fractional CO2 Laser

Group Type: ACTIVE_COMPARATOR

fractional CO2 laser

Intervention Type: DEVICE

single pass of fractional CO2 laser on the other side of the face

Interventions

short pulse and Q-switched ND-YAG laser with topical carbon

application of topical carbon cream, followed by two passes of short pulse 1064 ND-YAG, then one pass of Q-switched 1064 ND-YAG on one side of the face

Intervention Type: DEVICE

fractional CO2 laser

single pass of fractional CO2 laser on the other side of the face

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Participants who are more than 18 years old with the large facial pores and are aware of their problem and seeking treatment

Exclusion Criteria

• • Previous laser therapy, chemical peeling, microdermabrasion or cosmetic procedure for the face.

• Patients with any contraindication to laser therapy such as photosensitive diseases, skin malignancies, patients on oral retinoids.
• Keloid-forming tendency.
• Local or systemic treatment for skin pores in the previous 3 months
• Connective tissue disease or the use of immunosuppressive medications.
• Pregnancy.
• Present or past history of herpes labialis.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Dina Saadi

principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Kasr Alainy

Cairo, , Egypt

Countries

Egypt

Other Identifiers

las49

Identifier Type: -

Identifier Source: org_study_id