COVID - AirPollution

NCT ID: NCT04463862

Last Updated: 2021-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

660 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-04

Study Completion Date

2021-06-01

Brief Summary

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Epidemiological data have related particulate matter (PM), nitrogen dioxide (NO2) and ozone (O3) to COVID-19 morbidity and mortality at the population level. Air pollution may be related to an increase in the COVID-19 severity and lethality through its impact on chronic diseases such as cardiovascular and respiratory diseases and diabetes that are also the main comorbidities associated with COVID-19. Epidemiological studies using individual data are needed to provide more precise estimate of the association between air pollution exposure and COVID-19. In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of air pollutants at the residential address during the previous two years. In addition, the investigators will explore the relationship between short-term variations in air pollutants, relative humidity, temperature, UV radiations, pollen and the occurrence of COVID-19.

Detailed Description

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Conditions

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COVID-19 Confirmed Cases COVID-19 Mortality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient over 60 years old (or dementia patient over 50 years old)
* Patient hospitalized in a geriatric department over the period from 2020/01/01 to 2020/06/01
* Patient who underwent RT-PCR SARS-CoV-2
* Patient (or trusted person/ legal guardian/curator, if applicable) who has given consent to the re-use of his/her data (patient data) for research purposes

Exclusion Criteria

None
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frédéric BLANC, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpitaux Universitaires de Strasbourg

Locations

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Unité de neurologie-gériatrie, Hôpital Erasme, Cliniques Universitaires de Bruxelles

Brussels, , Belgium

Site Status

Unité de soins palliatifs gériatriques, Centre Hospitalier Départemental de Bischwiller

Bischwiller, , France

Site Status

Service de Gériatrie, Centre Hospitalier Départemental de Vendée

La Roche-sur-Yon, , France

Site Status

Service de médecine aigüe gériatrique, Hôpital Nord Laennec, Hôpitaux Universitaires de Nantes

Nantes, , France

Site Status

Service de Gériatrie, Hôpitaux Bichat et Bretonnaux, Assistance Publique des Hôpitaux de Paris

Paris, , France

Site Status

Service de Médecine Interne et Gériatrie, Hôpitaux Universitaires de Reims

Reims, , France

Site Status

Service de Gériatrie, Hôpital de la Robertsau, Hôpitaux Universitaires de Strasbourg

Strasbourg, , France

Site Status

Service de médecine gériatrique, Hôpitaux Universitaires de Tours

Tours, , France

Site Status

Countries

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Belgium France

Other Identifiers

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7922

Identifier Type: -

Identifier Source: org_study_id

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