Locoregional Surgery of the Primary Tumor in de Novo Stage IV Breast Cancer Patients
NCT ID: NCT04456855
Last Updated: 2020-07-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
358 participants
OBSERVATIONAL
2019-09-01
2021-07-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Locoregional surgery
Locoregional surgery
Patients had pathologically confirmed operable stage IV breast infiltrating carcinoma at initial presentation, and had locoregional surgery for the breast cancer.
No surgery
No interventions assigned to this group
Interventions
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Locoregional surgery
Patients had pathologically confirmed operable stage IV breast infiltrating carcinoma at initial presentation, and had locoregional surgery for the breast cancer.
Eligibility Criteria
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Inclusion Criteria
* ECOG-PS 0-2.
* Bone marrow, liver and kidney should be fully functional.
* Patients received the locoregional surgery of the primary tumor in de novo in our center, or didn't received the locoregional surgery of the primary tumor in de novo.
* For the patient who accepted systematic treatment before operation, the systematic treatment must be administered within a year since diagnosed.
Exclusion Criteria
* Patients who can't plan for follow-up effectively and regularly.
* Multiple liver metastasis and ALT/AST four times higher than normal at patients' first diagnosis.
18 Years
75 Years
FEMALE
No
Sponsors
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Sun Yat-sen University
OTHER
First People's Hospital of Foshan
OTHER
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
Responsible Party
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Herui Yao
Principal Investigator
Principal Investigators
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Herui Yao, PhD
Role: STUDY_CHAIR
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Jun Tang, PhD
Role: PRINCIPAL_INVESTIGATOR
Sun Yat-sen University
Guolin Ye, PhD
Role: PRINCIPAL_INVESTIGATOR
First People's Hospital of Foshan
Locations
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First People's Hospital of Foshan
Foshan, Guangdong, China
Sun Yat-Sen Memorial Hospital of Sun Yat-sen
Guangzhou, Guangdong, China
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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References
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Yu Y, Hong H, Wang Y, Fu T, Chen Y, Zhao J, Chen P, Cai R, Tan Y, He Z, Ren W, Zhou L, Huang J, Tang J, Ye G, Yao H. Clinical Evidence for Locoregional Surgery of the Primary Tumor in Patients with De Novo Stage IV Breast Cancer. Ann Surg Oncol. 2021 Sep;28(9):5059-5070. doi: 10.1245/s10434-021-09650-3. Epub 2021 Feb 3.
Other Identifiers
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SYSEC-KY-2018-018
Identifier Type: -
Identifier Source: org_study_id
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