Microwave Ablation for Pulmonary Metastases From Colorectal Cancer

NCT ID: NCT02502630

Last Updated: 2016-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-06-30

Study Completion Date

2015-07-31

Brief Summary

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(MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.

Detailed Description

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From June 2010 to June 2015, 48 unresectable lesions in 32 patients with pulmonary metastases from colorectal cancer were selected for CT-guided microwave ablation. Patients were scheduled for a 1 and 3 month CT follow-up to evaluate lesion diameter.We retrospectively evaluated CT-guided percutaneous microwave (MW) ablation safety and efficacy in pulmonary metastases from colorectal cancer.

Conditions

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Colorectal Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treated with microwave ablation

Patients undergoing MWA for pulmonary metastases from colorectal cancer.

Group Type EXPERIMENTAL

microwave ablation

Intervention Type DEVICE

pulmonary metastases from colorectal cancer are destructed/ablated using microwave ablation

Interventions

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microwave ablation

pulmonary metastases from colorectal cancer are destructed/ablated using microwave ablation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Unresectable pulmonary metastases from colorectal cancer.
* diagnosis by CT, and confirmed by percutaneous puncture biopsy.
* Age range 18-70 years old.
* Eastern Cooperative Oncology Group performance status 0-1.
* Life expectancy of more than 3 months.
* Adequate organ function.

Exclusion Criteria

* Resectable lung metastases.
* Life expectancy less than 3 months
* Patients with cardiac pacemaker, cerebral aneurysm clips, implanted electronic instruments or other metal materials.
* Coagulopathy with platelet count less than 50000.
* Active infectious disease.
* Age below 18 years.
* Pregnancy of breastfeeding.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First People's Hospital of Changzhou

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jingting Jiang, PD

Role: STUDY_DIRECTOR

The First People's Hospital of Changzhou

References

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Cheng G, Shi L, Qiang W, Wu J, Ji M, Lu Q, Li X, Xu B, Jiang J, Wu C. The safety and efficacy of microwave ablation for the treatment of CRC pulmonary metastases. Int J Hyperthermia. 2018 Jun;34(4):486-491. doi: 10.1080/02656736.2017.1366553. Epub 2017 Nov 16.

Reference Type DERIVED
PMID: 28847194 (View on PubMed)

Other Identifiers

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CRC-MW-001

Identifier Type: -

Identifier Source: org_study_id

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