A Follow-up of the Influencing Factors of Dyskinesia in Patients With Parkinson's Disease

NCT ID: NCT04453995

Last Updated: 2020-07-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-05

Study Completion Date

2022-06-01

Brief Summary

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Parkinson' patients who have not had dyskinesia would be observed for 2 years in a multicenter prospective study with the purposes to clarify the predicting factors of dyskinesia.

Detailed Description

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Parkinson' patients with daily levodopa dosage above 200mg and no dyskinesia would be recruited into the study. They would be observed for two years for analyzed the predicting factors of dyskinesia. At the baseline, demographic information, Clinical information, blood sample, picture of tongure coating would be collected at the baseline. All participants were evaluated every three months for two years. The severity of motor symptoms were evaluated every 6 months.

Conditions

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Parkinson Disease Dyskinesias

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

\- 1) Patients have been clinically diagnosed with Parkinson disease at the recruitment.

2\) Patients have received Levodopa treatment with the daily dosage above 200mg.

Exclusion Criteria

* 1\) be suspicious of atypical Parkinson or other Parkinson syndrome. 2) have experienced dyskinesia. 3) incorporation to the investigation
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Municipal Hospital of Traditional Chinese Medicine

OTHER

Sponsor Role collaborator

Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University

OTHER

Sponsor Role collaborator

Second Affiliated Hospital of Soochow University

OTHER

Sponsor Role collaborator

The Affiliated BenQ Hospital of Nanjing Medical University

UNKNOWN

Sponsor Role collaborator

The Affiliated Hospital of Qingdao University

OTHER

Sponsor Role collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

Sponsor Role collaborator

Zhejiang Provincial Tongde Hospital

OTHER

Sponsor Role collaborator

Shaoxing Hospital of Traditional Chinese medicine

UNKNOWN

Sponsor Role collaborator

The First People Hospital of Hangzhou Lin An District

UNKNOWN

Sponsor Role collaborator

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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zhenguo Liu, Ph.D.

Role: STUDY_CHAIR

Xinhua hosipital affiliated to Shanghai Jiaotong university school of medicine

Locations

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Xinhua hospital affiliated to Shanghai jiaotong university school of medicine

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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XH-19-014

Identifier Type: -

Identifier Source: org_study_id

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