Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
NCT ID: NCT04436913
Last Updated: 2022-08-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
54 participants
INTERVENTIONAL
2021-01-16
2022-01-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
NCT04446390
Effectiveness of Different Preventive Regimens in Cariogram Parameters and DMF Scores of High Caries Risk Patients: A Randomized Control Trial
NCT04032184
Efficacy and Cost-effectiveness of Different Caries Preventive Protocols
NCT05962632
Effect of Nano Hydroxy Apatite Varnish and Potassium Nitrate Gel on the MIH-affected Permanent Teeth
NCT06896565
Cariostatic and Remineralizing Effects of Three Different Dental Varnishes
NCT04887389
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Dental caries can be prevented by conducting appropriate measures; therefore, it is crucial to identify those who are most likely to have dental caries by caries risk assessment and giving them the essential preventive measures. Though some caries preventive measures have showed success in descriptive clinical trials, there is little information on their practicality with high caries risk groups in everyday usage.
Oral health is an essential part of general well being, people have used herbs in order to prevent dental diseases for centuries. In 2008 the Federal Council of Dentistry approved the use of medicinal plants for oral healthcare.
Medicinal plants can heal bacterial diseases as it is full of antimicrobial agents. They are becoming more popular than chemicals due to the side effects of synthetic antibiotics and the antibiotic resistance in microorganisms.
Studies propose that herbal extracts are highly effective against significant microorganism which cause dental caries like Streptococcus mutans. Herbal toothpaste decreases dental caries through combined effects of antibacterial agents, oral acid neutralisers and decreased plaque bacterial enzyme inhibitors present in the herbal toothpaste.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
preventive regimen using Herbal toothpaste(Himalaya)
The regimen includes herbal toothpaste containing "Neem , Miswak , Babool and Pomegranate" (Himalaya Complete Care).
Himalaya complete care toothpaste
Herbal toothpaste as a part of a caries preventive regimen
preventive regimen using Fluoride based toothpaste (Signal).
Participants will be using fluoride-based toothpaste (Signal), (1450 ppm sodium fluoride)
Signal toothpaste
fluoride based toothpaste as a part of a caries preventive regimen
Fluoride toothpaste and fluoride varnish
Participants will be using fluoride-based toothpaste (Signal), (1450 ppm sodium fluoride) and fluoride varnish
Signal toothpaste and fluoride varnish
application of fluoride varnish and using fluoride based toothpaste
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Himalaya complete care toothpaste
Herbal toothpaste as a part of a caries preventive regimen
Signal toothpaste
fluoride based toothpaste as a part of a caries preventive regimen
Signal toothpaste and fluoride varnish
application of fluoride varnish and using fluoride based toothpaste
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Age range 15-50 years.
* Patients with high caries risk assessment due to increased cariogenic bacteria according to Cariogram.
* low fermentable carbohydrates diet patient
* Not under antibiotic therapy either at the time of the study or up to the last month before the start of the study.
Exclusion Criteria
* Cariogenic diet patient.
* Extreme plaque accumulation and periodontal problems
* Participants with a history of allergy to any of the drugs or chemicals used in the study.
* Patients on any antibiotics during the past month
15 Years
50 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Cairo University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Hoda Abdelmeguid Mohamed Fathy Ismail Sabry
Principal Investigator , Master degree student, Conservative Dentistry Department, Faculty of Dentistry, Cairo University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Cairo university, Faculty of oral and dental medicine
Cairo, , Egypt
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Himalaya complete care
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.