Anticaries Potential and Fluorosis Risk From Different Fluoride Toothpastes
NCT ID: NCT01589991
Last Updated: 2013-10-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
24 participants
INTERVENTIONAL
2011-01-31
2013-07-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
SINGLE
Study Groups
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Non-fluoride toothpaste
Toothpaste
The volunteers brushed their teeth with 0.3 g of the assigned toothpastes, 3x/day.
Toothpaste 550 µg F/g (NaF/SiO2)
Toothpaste
The volunteers brushed their teeth with 0.3 g of the assigned toothpastes, 3x/day.
Toothpaste 1100 µg F/g (NaF/SiO2)
Toothpaste
The volunteers brushed their teeth with 0.3 g of the assigned toothpastes, 3x/day.
Toothpaste 1450 µg F/g (MFP/CaCO3)
Toothpaste
The volunteers brushed their teeth with 0.3 g of the assigned toothpastes, 3x/day.
Interventions
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Toothpaste
The volunteers brushed their teeth with 0.3 g of the assigned toothpastes, 3x/day.
Eligibility Criteria
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Inclusion Criteria
* Good oral health
3 Years
4 Years
ALL
Yes
Sponsors
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University of Campinas, Brazil
OTHER
Responsible Party
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Livia Maria Andaló Tenuta
Assistant Professor, Biochemistry and Cariology
Principal Investigators
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Livia MA Tenuta, PhD
Role: STUDY_CHAIR
Piracicaba Dental School, University of Campinas
Locations
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Piracicaba Dental School, University of Campinas
Piracicaba, São Paulo, Brazil
Countries
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References
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Cury JA, do Amaral RC, Tenuta LM, Del Bel Cury AA, Tabchoury CP. Low-fluoride toothpaste and deciduous enamel demineralization under biofilm accumulation and sucrose exposure. Eur J Oral Sci. 2010 Aug;118(4):370-5. doi: 10.1111/j.1600-0722.2010.00745.x.
Lima TJ, Ribeiro CC, Tenuta LM, Cury JA. Low-fluoride dentifrice and caries lesion control in children with different caries experience: a randomized clinical trial. Caries Res. 2008;42(1):46-50. doi: 10.1159/000111749. Epub 2007 Nov 27.
Cury JA, Tenuta LM, Ribeiro CC, Paes Leme AF. The importance of fluoride dentifrices to the current dental caries prevalence in Brazil. Braz Dent J. 2004;15(3):167-74. doi: 10.1590/s0103-64402004000300001. Epub 2005 Mar 18.
Paes Leme AF, Dalcico R, Tabchoury CP, Del Bel Cury AA, Rosalen PL, Cury JA. In situ effect of frequent sucrose exposure on enamel demineralization and on plaque composition after APF application and F dentifrice use. J Dent Res. 2004 Jan;83(1):71-5. doi: 10.1177/154405910408300114.
Cury JA, Francisco SB, Simoes GS, Del Bel Cury AA, Tabchoury CP. Effect of a calcium carbonate-based dentifrice on enamel demineralization in situ. Caries Res. 2003 May-Jun;37(3):194-9. doi: 10.1159/000070444.
Cury JA, Simoes GS, Del Bel Cury AA, Goncalves NC, Tabchoury CP. Effect of a calcium carbonate-based dentifrice on in situ enamel remineralization. Caries Res. 2005 May-Jun;39(3):255-7. doi: 10.1159/000084807.
Cury JA, Oliveira MJ, Martins CC, Tenuta LM, Paiva SM. Available fluoride in toothpastes used by Brazilian children. Braz Dent J. 2010;21(5):396-400. doi: 10.1590/s0103-64402010000500003.
Martins CC, Oliveira MJ, Pordeus IA, Cury JA, Paiva SM. Association between socioeconomic factors and the choice of dentifrice and fluoride intake by children. Int J Environ Res Public Health. 2011 Nov;8(11):4284-99. doi: 10.3390/ijerph8114284. Epub 2011 Nov 10.
Other Identifiers
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FOPBioq002
Identifier Type: -
Identifier Source: org_study_id