Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
81 participants
INTERVENTIONAL
2020-09-01
2021-12-30
Brief Summary
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Detailed Description
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The present clinical trial will be conducted to reject or accept the null hypothesis that using Licorice extract mouth wash in addition to standard preventive measures will not differ from using standard preventive measures alone in preventing incidence of new carious lesions.
PICOTS:
P: Population with high caries risk patients
I: Use of licorice.
I2: Use of chlorhexidine
C: Use of standard preventive measures (tooth brushing, tooth paste, interdental cleaning).
O.1: Primary outcome is incidence of new carious lesions
T: Time for measurement is 12 months
S: A Randomized controlled clinical trial (Parallel study)
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Licorice
licorice is one of the natural products that is listed by the Food and Drug Administration (FDA) as GRAS (generally regarded as safe) when used as food flavoring and sweetening agent which has an antimicrobial, anti-inflammatory and antiviral activity.
Licorice
Natural herbal product
Chlorhexidine
The "gold standard" of oral therapeutics is Chlorhexidine due to its prolonged broad- spectrum antimicrobial effect.
Licorice
Natural herbal product
Control Group
Participants in this group will follow only the standard preventive measures which is brushing twice a day after breakfast and before bed time and daily flossing interdentally before bed time. (No Mouthwash is used)
No interventions assigned to this group
Interventions
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Licorice
Natural herbal product
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* 18-25 years,
* Males or females,
* Medically free patients,
* Patients approving to participate in the study.
Exclusion Criteria
* Patients had history of professional cleaning in the last 15 days,
* Patients with exposed pulp,
* Evidence of parafunctional habits,
* Patients with developmental dental anomalies,
* Patients undergoing or will start orthodontic treatment,
* Patients with removable prosthesis,
* Periapical Abscess or Fistula.
18 Years
25 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Sara Mohammed Ahmed Mady
Principal Investigator
Locations
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Conservative and Esthetic Dentistry Department-Faculty of Dentistry- Cairo University
Cairo, Choose Any State/Province, Egypt
Countries
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Other Identifiers
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18941
Identifier Type: -
Identifier Source: org_study_id
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