Oxytocin's Effects on Face Attentional Processing

NCT ID: NCT04413786

Last Updated: 2022-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-14

Study Completion Date

2021-12-26

Brief Summary

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To investigate whether intranasal oxytocin (24IU) treatment has a regulatory effect on attentional processing of emotional faces.

Detailed Description

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In a placebo-controlled double-blind between-subject design experiment, investigators plan to investigate the effect of oxytocin treatment on attentional processing of emotional faces. Subjects complete questionnaires in Chinese versions before treatment administration, including the Beck Depression Inventory, Autism Spectrum Quotient , Trait Anxiety Inventory, Toronto Alexithymia Scale, Multidimentional Assessment of Interoceptive Awareness. This experiment consists of two tasks including Emotional Face Cue-target Task and Visual Search Task. In the first task, subjects need to make a response to judge the position of target after a cue-target is presented. In the second task, subjects are asked to search the target "U" or inverted "U" placed on the nose of emotional/neutral faces and make an choices based on their oorientation. During these phases, subjects' response accuracy, response time and electrophysiological activity (ERP) are recorded.

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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oxytocin group

male subjects with oxytocin treatment

Group Type EXPERIMENTAL

oxytocin treatment

Intervention Type DRUG

intranasal administration of oxytocin (24IU)

placebo group

male subjects with placebo treatment

Group Type PLACEBO_COMPARATOR

placebo treatment

Intervention Type DRUG

intranasal administration of placebo (24IU)

Interventions

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oxytocin treatment

intranasal administration of oxytocin (24IU)

Intervention Type DRUG

placebo treatment

intranasal administration of placebo (24IU)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion Criteria

* history of head injury
* medical or psychiatric illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Electronic Science and Technology of China

OTHER

Sponsor Role lead

Responsible Party

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Shuxia Yao

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shuxia Yao, Doctor

Role: STUDY_DIRECTOR

University of Electronic Science and Technology

Locations

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School of life science and technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

Site Status

Countries

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China

Other Identifiers

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UESTC-neuSCAN-71

Identifier Type: -

Identifier Source: org_study_id

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