Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
27000 participants
OBSERVATIONAL
2020-04-23
2020-05-01
Brief Summary
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Detailed Description
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The SARS-CoV-2-CZ-Preval study is aiming at quantification of the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on direct detection of SARS-CoV- 2, including individuals with a subclinical course of the disease.
Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Population area cohort - Control Cohort
A population cohort of asymptomatic individuals (only adults). This is a representative sample of the population, which are part of the research project of Institute for Clinical and Experimental Medicine and Czech Academy of Sciences. The second subsample included individuals from the official household survey of Czech Statistical Office. This cohort allowed better comparative analysis of other population cohorts from specific geographical areas.
SARS-CoV-2 diagnostic rapid test
The rapid test detects the presence of antibodies against SARS-CoV-2 in the IgM and IgG class by the immunochromatographic reaction. It cannot detect early infection, the antibodies will probably appear two weeks after possible infection. The collection will be performed by finger puncture.
Population cohort from specific geographical areas
This cohort is based on epidemiologically defined demographic parameters. These are populations from the following geographical areas:
Brno and the South Moravian Region; Praha; Olomouc; Litoměřice; Litovel and Uničov.
SARS-CoV-2 diagnostic rapid test
The rapid test detects the presence of antibodies against SARS-CoV-2 in the IgM and IgG class by the immunochromatographic reaction. It cannot detect early infection, the antibodies will probably appear two weeks after possible infection. The collection will be performed by finger puncture.
Quantitative analysis of SARS-CoV-2 antibodies
The subsample from Olomouc region (Olomouc, Uničov, Litovel) is based on venous blood sampling and archiving for subsequent quantitative analysis of SARS-CoV-2 antibodies. These tests detect immunoglobulins M and G (IgM and IgG).
Chronically ill patients cohort
A cohort of chronically ill people enrolled by Institute for Clinical and Experimental Medicine with chronic cardiovascular problems, hypertension, or diabetes.
SARS-CoV-2 diagnostic rapid test
The rapid test detects the presence of antibodies against SARS-CoV-2 in the IgM and IgG class by the immunochromatographic reaction. It cannot detect early infection, the antibodies will probably appear two weeks after possible infection. The collection will be performed by finger puncture.
Interventions
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SARS-CoV-2 diagnostic rapid test
The rapid test detects the presence of antibodies against SARS-CoV-2 in the IgM and IgG class by the immunochromatographic reaction. It cannot detect early infection, the antibodies will probably appear two weeks after possible infection. The collection will be performed by finger puncture.
Quantitative analysis of SARS-CoV-2 antibodies
The subsample from Olomouc region (Olomouc, Uničov, Litovel) is based on venous blood sampling and archiving for subsequent quantitative analysis of SARS-CoV-2 antibodies. These tests detect immunoglobulins M and G (IgM and IgG).
Eligibility Criteria
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Inclusion Criteria
* residing in The Czech Republic
* demographic criteria: (i) persons aged 8-17 (specific children's cohort), (ii) persons aged 18-89
* clinical criteria: (i) without acute health problems (ii) without a confirmed diagnosis of COVID-19
* geographic criteria: according to a particular cohort definition
8 Years
89 Years
ALL
Yes
Sponsors
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Ministry of Health, Czech Republic
OTHER_GOV
Palacky University
OTHER
Masaryk University
OTHER
University of Ostrava
OTHER
Faculty of Military Health Sciences, University of Defence in Brno
UNKNOWN
Faculty of Health Studies, J. E. Purkyně University in Ústí nad Labem
UNKNOWN
Charles University, Czech Republic
OTHER
Institute for Clinical and Experimental Medicine
OTHER_GOV
General University Hospital, Prague
OTHER
University Hospital Olomouc
OTHER
Brno University Hospital
OTHER
Krajská zdravotní, a.s., Ústí nad Labem Region Hospitals
UNKNOWN
Military University Hospital, Prague
OTHER
Masaryk Memorial Cancer Institute
OTHER
Czech Academy of Sciences
OTHER
Czech Statistical Office
UNKNOWN
Faculty of Medicine in Hradec Králové, Charles University
UNKNOWN
Institute of Health Information and Statistics of the Czech Republic
OTHER_GOV
Responsible Party
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Principal Investigators
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Roman Chlíbek, Prof.
Role: STUDY_DIRECTOR
University of Defence in Brno
Rastislav Maďar, Assoc. Prof.
Role: STUDY_DIRECTOR
University of Ostrava, Faculy of Medicine
Marián Hajdúch, Assoc. Prof.
Role: STUDY_DIRECTOR
Institute of Molecular and Translational Medicine
Ladislav Dušek, Prof.
Role: STUDY_DIRECTOR
Institute of Health Information and Statistics of the Czech Republic
Roman Prymula, Prof.
Role: STUDY_CHAIR
Ministry of Health, Czech Republic
Jarmila Rážová, M.D.; Ph.D.
Role: STUDY_CHAIR
Ministry of Health, Czech Republic
Věra Adámková, Prof.
Role: PRINCIPAL_INVESTIGATOR
Institute for Clinical and Experimental Medicine
Aleksi Šedo, Prof.
Role: PRINCIPAL_INVESTIGATOR
Charles University, First Faculty of Medicine
Vladimír Černý, Prof.
Role: PRINCIPAL_INVESTIGATOR
Charles University, Faculty of Medicine in Hradec Králové
Jaroslav Štěrba, Prof.
Role: PRINCIPAL_INVESTIGATOR
Brno University Hospital
David Feltl, Prof.
Role: PRINCIPAL_INVESTIGATOR
General University Hospital, Prague
Martin Repko, Prof.
Role: PRINCIPAL_INVESTIGATOR
Masaryk University, Faculty of Medicine
Dalibor Valík, Prof.
Role: PRINCIPAL_INVESTIGATOR
Masaryk Memorial Cancer Institute
Zdeněk Havel, Assoc. Prof.
Role: PRINCIPAL_INVESTIGATOR
J. E. Purkyně University in Ústí nad Labem, Faculty of Health Studies
Locations
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Institute of Health Information and Statistics of the Czech Republic
Prague, , Czechia
Countries
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Other Identifiers
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UZIS 2020/1
Identifier Type: -
Identifier Source: org_study_id
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