The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

NCT ID: NCT00981071

Last Updated: 2010-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-05-31

Study Completion Date

2010-04-30

Brief Summary

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The aim is to evaluate the time of positive conversion after exposure to smear positive pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.

Detailed Description

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In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT), QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3 months as treatment of latent TB.

Conditions

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Tuberculosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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A platoon with TB outbreak

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All soldiers who assigned to the military platoon where a tuberculosis outbreak occurred

Exclusion Criteria

* Soldiers who could not complete study or refused the study protocol
Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Armed Forces Capital Hospital, Republic of Korea

OTHER_GOV

Sponsor Role lead

Responsible Party

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Armed Forces Capital Hospital

Principal Investigators

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Jae-Joon Yim, MD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Other Identifiers

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QFTconversion

Identifier Type: -

Identifier Source: org_study_id

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