Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised Patients

NCT ID: NCT00962676

Last Updated: 2012-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

140 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2010-12-31

Brief Summary

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For diagnosis of active tuberculosis, interferon-γ release assay based mycobacterium tuberculosis specific antigen may show higher sensitivity than tuberculin skin test in immunocompromised patients. Therefore, interferon-γ release assay have a role as a rapid diagnostic adjunctive methods for active tuberculosis in immunocompromised patients.

Detailed Description

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Conditions

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Tuberculosis

Study Groups

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immunocompromised group

No interventions assigned to this group

non-immunocompromised group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patient suspicious of active tuberculosis with immunocompromised condition
* Immunocompromised condition patients with

1. solid cancer with chemotherapy
2. hematologic malignancy
3. organ transplantation
4. immunosuppressant
5. ESRD on renal replacement therapy
6. diabetes
7. advanced liver cirrhosis

Exclusion Criteria

* Patients with

1. less than 20 years
2. who don't agree the participation of study
3. hypersensitivity history to tuberculin
4. pregnancy
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Yonsei Univ.

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2009-0129

Identifier Type: -

Identifier Source: org_study_id

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