Non-microradical Resection Margin as a Predictor for Recurrence After Complete Mesocolic Excision

NCT ID: NCT04395534

Last Updated: 2020-05-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

276 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-06-01

Study Completion Date

2020-03-15

Brief Summary

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The study aim to investigate the value of the current definition of microradical resection margin in colon cancer. Is the distance from tumor tissue to resection margin and the site of any clinically prognostic importance if complete mesocolic excision has been performed.

Detailed Description

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Conditions

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Colon Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Complete mesocolic excision

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Undergoing elective curative intended complete mesocolic excision for primary colon adenocarcinoma at Nordsjællands Hospital in Hillerød, Denmark
* International Union Against Cancer (Union Internationale Contre le Cancer - UICC) stage III - pT1-4, pN1-2 cM0 (gastroepiploic and infrapyloric lymph node metastases are not considered as distant metastases)
* Resident in Denmark at the time of surgery.

Exclusion Criteria

* Patients who did not undergo macroradical resections
* Synchronous colorectal cancer
* Venous invasion at central venous ligation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Claus Anders Bertelsen, PhD, MD

OTHER

Sponsor Role lead

Responsible Party

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Claus Anders Bertelsen, PhD, MD

Consultant Colorectal Surgeon, Associate Professor, Head of Research Department of Surgery

Responsibility Role SPONSOR_INVESTIGATOR

References

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Gundestrup AK, Olsen ASF, Ingeholm P, Bols B, Kleif J, Bertelsen CA. Nonmicroradical Resection Margin as a Predictor of Recurrence in Patients With Stage III Colon Cancer Undergoing Complete Mesocolic Excision: A Prospective Cohort Study. Dis Colon Rectum. 2022 May 1;65(5):683-691. doi: 10.1097/DCR.0000000000001996.

Reference Type DERIVED
PMID: 34933419 (View on PubMed)

Other Identifiers

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R1 - CME

Identifier Type: -

Identifier Source: org_study_id

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