Colchicine Has Anti-diabetic Effect

NCT ID: NCT04377321

Last Updated: 2020-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-10

Study Completion Date

2020-05-02

Brief Summary

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Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

Detailed Description

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Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.

The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only.

The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin

Conditions

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Treatment Adherence

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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group 1 on cochicine

The first group patients received colchicine 0.5 twice daily for 6 months

Colchicine Tablets

Intervention Type DRUG

colchicine tabletes for 6 months

group 2 on glucophage 1 gm twice daily

second group received glucophage 1gm twice daily for 6 months

Colchicine Tablets

Intervention Type DRUG

colchicine tabletes for 6 months

group 3 control

the third group patients were on diet only for 6 months

Colchicine Tablets

Intervention Type DRUG

colchicine tabletes for 6 months

Interventions

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Colchicine Tablets

colchicine tabletes for 6 months

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* type 2 diabetes newly diagnosed age 35- 55 years

Exclusion Criteria

* severe anemia hypothyroidism and hyperthyroidism moderate to severe liver or kidney disease
Minimum Eligible Age

35 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ministry of Health and Population, Egypt

OTHER_GOV

Sponsor Role lead

Responsible Party

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mahmoud younis

consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mahmoud Younis

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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[email protected]

Identifier Type: -

Identifier Source: org_study_id

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