Vinegar Co-ingestion in Type 2 Diabetes

NCT ID: NCT01279317

Last Updated: 2011-10-03

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2011-03-31

Brief Summary

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The main objective of this study is to assess the acute effect of co-ingested vinegar on postprandial plasma glucose levels in type 2 diabetes patients.

Detailed Description

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Plasma glucose and insulin concentrations are assessed over the 2 hr period following ingestion of carbohydrate-rich beverage with or without added vinegar.

Conditions

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Type 2 Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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vinegar co-ingestion

25 ml vinegar is added to glucose containing beverage

Group Type EXPERIMENTAL

vinegar co-ingestion

Intervention Type DIETARY_SUPPLEMENT

25 ml vinegar (1 g acetic acid) co-ingested with a glucose-containing beverage

Placebo co-ingestion

25 ml vinegar is substituted by 25 ml water

Group Type PLACEBO_COMPARATOR

placebo co-ingestion

Intervention Type DIETARY_SUPPLEMENT

25 ml water co-ingested with a glucose-containing beverage

Interventions

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placebo co-ingestion

25 ml water co-ingested with a glucose-containing beverage

Intervention Type DIETARY_SUPPLEMENT

vinegar co-ingestion

25 ml vinegar (1 g acetic acid) co-ingested with a glucose-containing beverage

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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vinegar acetic acid

Eligibility Criteria

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Inclusion Criteria

* male type 2 diabetes
* overweight or obese
* 40-70 yrs

Exclusion Criteria

* incident cardiovascular events during last year
* peptic ulcer, duodenal ulcer, oesophageal reflux
* antacids, H2 receptor blocker, proton pump inhibitors, NSAIDS, prokinetic agents
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Maastricht University Medical Centre

Maastricht, Limburg, Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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MEC 10-3-035

Identifier Type: -

Identifier Source: org_study_id