MR7T-Healthy-PTX : Brain Exploration in Magnetic Resonance Imaging in Parallel Transmission Mode (pTX) at 7 Tesla

NCT ID: NCT04369755

Last Updated: 2022-01-27

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-06-25
• Study Completion Date: 2022-12-31

Brief Summary

Magnetic resonance imaging (MRI) is a non-invasive imaging modality used in routine clinical practice for clinical diagnosis by visualizing the anatomical structure and in vivo function of certain organs. The development of ultra-high field MRI systems with 7.0-T or higher, gives access to a new field of exploration of the human body by improving the speed of acquisition but also a better signal-to-noise ratio (SNR) and better resolution. In order to fully exploit the potential of these ultra-high field MRI scanners, various technical issues must be adressed. Indeed, the non-uniformity of the transmission field is one of them leading to non-uniform images with spatially varying contrast. Thus the pTX (parallel transmission) mode using multiple transmission channels allows spatial and temporal control over the RF waves.

Conditions

MRI; PTX; BRAIN; 7 TESLA

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

MRI

A MRI on PTX mode will be done on healthy subjects (approx. 90 min of sequences)

Group Type: OTHER

MRI

Intervention Type: OTHER

A MRI in PTX mode will be done on healthy subject (approx. 90 min of sequences)

Interventions

MRI

A MRI in PTX mode will be done on healthy subject (approx. 90 min of sequences)

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age ≥ 18 years old
• Subject with no MRI contraindications (metallic shine, pacemaker)
• Free subject, without guardianship or curatorship or subordination
• A person affiliated to or beneficiary of a social security scheme.
• Informed and signed consent by the healthy volunteer after clear and fair information about the study

Exclusion Criteria

• Subject with a contraindication to MRI (pregnancy, ocular metallic foreign body (accidental or other shrapnel); pacemaker (cardiac stimulator), implantable defibrillator, non MRI 7.0 T compatible neurostimulator, cochlear implants and generally any irremovably implanted electronic medical device; metallic heart valve, vascular clips formerly implanted on cranial aneurysm), metallic prostheses.
• Healthy volunteers suffering from claustrophobia
• Persons not benefiting from a Social Security scheme or not benefiting from it through a third party.
• Persons benefiting from reinforced protection, i.e. minors, pregnant and breastfeeding women, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social institution, adults under legal protection and finally, patients in emergency situations.
• Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception (hormonal/mechanical: per os, injectable, transcutaneous, implantable, intrauterine device, or surgical: tubal ligation, hysterectomy, total oophorectomy).

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Poitiers University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

CHU de Poitiers

Poitiers, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Rémy GUILLEVIN, Pr

Role: CONTACT

remy.guillevin@chu-poitiers.fr

05.49.44.17.91

Facility Contacts

Rémy GUILLEVIN

Role: primary

Other Identifiers

2019-A02689-48

Identifier Type: -

Identifier Source: org_study_id